Literature DB >> 26150624

Molten metal ocular burn: long-term outcome using simple limbal epithelial transplantation.

Shilpa Das1, Sayan Basu2, Virender Sangwan2.   

Abstract

One day after molten aluminium had fallen into his right eye, a young man presented to our clinic with a vision of counting fingers at 1 m, conjunctival and corneal epithelial defects, and limbal involvement. He was diagnosed with grade 4 thermal burn and managed medically. Subsequently, the inflammation resolved, however, he developed pannus with conjunctivalisation and scarring of cornea suggestive of partial unilateral limbal stem cell deficiency. He was treated surgically with autologous simple limbal epithelial transplantation (SLET). Postoperatively, his vision improved along with corneal clarity. He achieved a best corrected vision of 20/50 at the last follow-up 27 months postsurgery, with maintenance of a healthy corneal epithelium. This case describes the different management strategies employed in two different stages of an ocular burn. It highlights the long-term success of SLET in a case of ocular surface thermal burn. 2015 BMJ Publishing Group Ltd.

Entities:  

Mesh:

Year:  2015        PMID: 26150624      PMCID: PMC4493204          DOI: 10.1136/bcr-2014-209272

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  10 in total

1.  A new classification of ocular surface burns.

Authors:  H S Dua; A J King; A Joseph
Journal:  Br J Ophthalmol       Date:  2001-11       Impact factor: 4.638

Review 2.  Limbal stem cell transplantation.

Authors:  Merle Fernandes; Virender S Sangwan; Srinivas K Rao; Surendra Basti; Mittanamalli S Sridhar; Aashish K Bansal; Harminder S Dua
Journal:  Indian J Ophthalmol       Date:  2004-03       Impact factor: 1.848

Review 3.  Management of ocular thermal and chemical injuries, including amniotic membrane therapy.

Authors:  Robert Fish; Richard S Davidson
Journal:  Curr Opin Ophthalmol       Date:  2010-07       Impact factor: 3.761

4.  Ocular surface reconstruction for thermal burns caused by fireworks.

Authors:  Jun Shimazaki; Kenji Konomi; Shigeto Shimmura; Kazuo Tsubota
Journal:  Cornea       Date:  2006-02       Impact factor: 2.651

5.  Evaluation of amniotic membrane transplantation as an adjunct to medical therapy as compared with medical therapy alone in acute ocular burns.

Authors:  Amol Tamhane; Rasik B Vajpayee; Nihar R Biswas; Ravindra M Pandey; Namrata Sharma; Jeewan S Titiyal; Radhika Tandon
Journal:  Ophthalmology       Date:  2005-09-29       Impact factor: 12.079

6.  Simple limbal epithelial transplantation (SLET): a novel surgical technique for the treatment of unilateral limbal stem cell deficiency.

Authors:  Virender S Sangwan; Sayan Basu; Sheila MacNeil; Dorairajan Balasubramanian
Journal:  Br J Ophthalmol       Date:  2012-02-10       Impact factor: 4.638

7.  In-vivo expansion of autologous limbal stem cell using simple limbal epithelial transplantation for treatment of limbal stem cell deficiency.

Authors:  Ikeda Lal; Bhavik Uttam Panchal; Sayan Basu; Virender S Sangwan
Journal:  BMJ Case Rep       Date:  2013-05-22

8.  Successful management of immunological rejection following allogeneic simple limbal epithelial transplantation (SLET) for bilateral ocular burns.

Authors:  Swapnil Bhalekar; Sayan Basu; Virender S Sangwan
Journal:  BMJ Case Rep       Date:  2013-03-14

9.  Successful autologous simple limbal epithelial transplantation (SLET) in previously failed paediatric limbal transplantation for ocular surface burns.

Authors:  Swapnil Bhalekar; Sayan Basu; Ikeda Lal; Virender S Sangwan
Journal:  BMJ Case Rep       Date:  2013-05-10

10.  Long-term restoration of damaged corneal surfaces with autologous cultivated corneal epithelium.

Authors:  G Pellegrini; C E Traverso; A T Franzi; M Zingirian; R Cancedda; M De Luca
Journal:  Lancet       Date:  1997-04-05       Impact factor: 79.321

  10 in total
  4 in total

1.  Preliminary results from the comparison of simple limbal epithelial transplantation with conjunctival limbal autologous transplantation in severe unilateral chronic ocular burns.

Authors:  Ritu Arora; Pallavi Dokania; Aditi Manudhane; Jawahar Lal Goyal
Journal:  Indian J Ophthalmol       Date:  2017-01       Impact factor: 1.848

Review 2.  Twenty years of limbal epithelial therapy: an update on managing limbal stem cell deficiency.

Authors:  Roberto Fernandez-Buenaga; Francesco Aiello; Sarah S Zaher; Andre Grixti; Sajjad Ahmad
Journal:  BMJ Open Ophthalmol       Date:  2018-08-10

Review 3.  Simple limbal epithelial transplantation: Current status and future perspectives.

Authors:  Catherine J Jackson; Inger T Myklebust Ernø; Håkon Ringstad; Kim A Tønseth; Darlene A Dartt; Tor P Utheim
Journal:  Stem Cells Transl Med       Date:  2019-12-04       Impact factor: 6.940

Review 4.  Economic, clinical and social impact of simple limbal epithelial transplantation for limbal stem cell deficiency.

Authors:  Praveen Thokala; Aastha Singh; Vijay Kumar Singh; Varsha M Rathi; Sayan Basu; Vivek Singh; Sheila MacNeil; Virender Singh Sangwan
Journal:  Br J Ophthalmol       Date:  2021-03-09       Impact factor: 5.908

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.