Literature DB >> 26150396

Concurrent thymoma, thymic carcinoma, and T lymphoblastic leukemia/lymphoma in an anterior mediastinal mass.

Junko Ito1, Akihiko Yoshida1, Akiko Miyagi Maeshima1, Kazuo Nakagawa2, Shun-ichi Watanabe2, Yukio Kobayashi3, Suguru Fukuhara3, Koji Tsuta4.   

Abstract

We report a case of a 62-year-old man with concurrent thymoma, thymic carcinoma, and T lymphoblastic leukemia/lymphoma. Computed tomography revealed a 5.5-cm anterior mediastinal mass, and surgical resection was performed. Histologically, the mass showed concurrent thymoma (type AB), thymic carcinoma, and T lymphoblastic leukemia/lymphoma. Lymphoma cells infiltrated in the left lung, pulmonary hilar lymph nodes, and involved bone marrow. The patient underwent chemotherapy for T lymphoblastic leukemia/lymphoma and achieved remission. One year after surgery, he remains free of both thymoma and thymic carcinoma, and T lymphoblastic leukemia/lymphoma remains complete remission under maintenance therapy. Thymoma and T lymphoblastic leukemia/lymphoma can combine in the same mass, although this is quite rare. At the time of the diagnosis of thymoma, additional attention should be directed toward lymphocytes in the background.
Copyright © 2015 Elsevier GmbH. All rights reserved.

Entities:  

Keywords:  T lymphoblastic leukemia/lymphoma; Thymic carcinoma; Thymoma; Thymus

Mesh:

Substances:

Year:  2015        PMID: 26150396     DOI: 10.1016/j.prp.2015.06.002

Source DB:  PubMed          Journal:  Pathol Res Pract        ISSN: 0344-0338            Impact factor:   3.250


  2 in total

Review 1.  Concurrent myasthenia gravis-related cervical thymoma in a patient with diffuse large B-cell lymphoma: a case report.

Authors:  Chutima Kunacheewa; Sattawut Wongwiangjunt; Sanya Sukpanichnant
Journal:  J Med Case Rep       Date:  2022-01-12

Review 2.  An overview on the differential diagnostics of tumors of the anterior-superior mediastinum: the pathologist's perspective.

Authors:  Mirella Marino; Stefano Ascani
Journal:  Mediastinum       Date:  2019-02-22
  2 in total

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