Literature DB >> 2615

Rapid gas chromatographic determination of underivatized theophylline in whole blood.

M Sheehan, P Haythorn.   

Abstract

A rapid gas chromatographic method for the determination of underivatized theophylline in whole blood is described. Theophylline is extracted from acidified blood and chromatographed directly using cyheptamide as an internal standard. Concentrations of the drug down to 2 mug/ml in blood could be determined with recoveries ranging from 90 to 110%.

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Year:  1976        PMID： 2615     DOI： 10.1016/0021-9673(76)80016-7

Source DB:  PubMed          Journal:  J Chromatogr


  4 in total

Review 1.  Clinical pharmacokinetics of theophylline.

Authors:  R I Ogilvie
Journal:  Clin Pharmacokinet       Date:  1978 Jul-Aug       Impact factor: 6.447

Review 2.  Drug interferences with plasma assays in therapeutic drug monitoring.

Authors:  S Yosselson-Superstine
Journal:  Clin Pharmacokinet       Date:  1984 Jan-Feb       Impact factor: 6.447

3.  Theophylline pharmacokinetics in advanced age.

Authors:  E J Antal; P A Kramer; S A Mercik; D J Chapron; I R Lawson
Journal:  Br J Clin Pharmacol       Date:  1981-11       Impact factor: 4.335

4.  Comparative pharmacokinetics of caffeine in young and elderly men.

Authors:  J Blanchard; S J Sawers
Journal:  J Pharmacokinet Biopharm       Date:  1983-04
  4 in total

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