Literature DB >> 26149051

Road blocks in making platelets for transfusion.

J N Thon1,2,3, D A Medvetz1,2, S M Karlsson3, J E Italiano1,2,3.   

Abstract

The production of laboratory-generated human platelets is necessary to meet present and future transfusion needs. This manuscript will identify and define the major roadblocks that must be overcome to make human platelet production possible for clinical use, and propose solutions necessary to accelerate development of laboratory-generated human platelets to market.
© 2015 International Society on Thrombosis and Haemostasis.

Entities:  

Keywords:  biomedical engineering; bioreactors; hematopoietic stem cells; megakaryocytes; platelets

Mesh：

Year:  2015        PMID： 26149051      PMCID： PMC5565795          DOI： 10.1111/jth.12942

Source DB:  PubMed          Journal:  J Thromb Haemost        ISSN： 1538-7836            Impact factor:   5.824


  72 in total

Review 1.  Platelet transfusion therapy.

Authors:  Sherrill J Slichter
Journal:  Hematol Oncol Clin North Am       Date:  2007-08       Impact factor: 3.722

2.  Alternatives to the use of fetal bovine serum: human platelet lysates as a serum substitute in cell culture media.

Authors:  Caroline Rauch; Elisabeth Feifel; Eva-Maria Amann; Hans Peter Spötl; Harald Schennach; Walter Pfaller; Gerhard Gstraunthaler
Journal:  ALTEX       Date:  2011       Impact factor: 6.043

3.  Three-dimensional system for the in vitro study of megakaryocytes and functional platelet production using silk-based vascular tubes.

Authors:  Isabella Pallotta; Michael Lovett; David L Kaplan; Alessandra Balduini
Journal:  Tissue Eng Part C Methods       Date:  2011-09-06       Impact factor: 3.056

Review 4.  Challenges and promises for the development of donor-independent platelet transfusions.

Authors:  Michele P Lambert; Spencer K Sullivan; Rudy Fuentes; Deborah L French; Mortimer Poncz
Journal:  Blood       Date:  2013-01-15       Impact factor: 22.113

5.  Transplantation of ex vivo expanded cord blood.

Authors:  Elizabeth J Shpall; Ralph Quinones; Roger Giller; Chan Zeng; Anna E Baron; Roy B Jones; Scott I Bearman; Yago Nieto; Brian Freed; Nancy Madinger; Christopher J Hogan; Vicki Slat-Vasquez; Peggy Russell; Betsy Blunk; Deborah Schissel; Elaine Hild; Janet Malcolm; William Ward; Ian K McNiece
Journal:  Biol Blood Marrow Transplant       Date:  2002       Impact factor: 5.742

6.  Metalloproteinase inhibitors improve the recovery and hemostatic function of in vitro-aged or -injured mouse platelets.

Authors:  Wolfgang Bergmeier; Peter C Burger; Crystal L Piffath; Karin M Hoffmeister; John H Hartwig; Bernhard Nieswandt; Denisa D Wagner
Journal:  Blood       Date:  2003-08-07       Impact factor: 22.113

7.  Induction of functional platelets from mouse and human fibroblasts by p45NF-E2/Maf.

Authors:  Yukako Ono; Yuhuan Wang; Hidenori Suzuki; Shinichiro Okamoto; Yasuo Ikeda; Mitsuru Murata; Mortimer Poncz; Yumiko Matsubara
Journal:  Blood       Date:  2012-07-31       Impact factor: 22.113

8.  Critical role for ERK1/2 in bone marrow and fetal liver-derived primary megakaryocyte differentiation, motility, and proplatelet formation.

Authors:  Alexandra Mazharian; Steve P Watson; Sonia Séverin
Journal:  Exp Hematol       Date:  2009-07-18       Impact factor: 3.084

9.  Infusion of megakaryocytic progenitor products generated from cord blood hematopoietic stem/progenitor cells: results of the phase 1 study.

Authors:  Jiafei Xi; Honghu Zhu; Daqing Liu; Xue Nan; Wen Zheng; Kaiyan Liu; Wei Shi; Lin Chen; Yang Lv; Fang Yan; Yanhua Li; Xiaoyan Xie; Yunfang Wang; Wen Yue; Xin Xu; Xiaofei Wei; Jun Zhu; Xiaojun Huang; Xuetao Pei
Journal:  PLoS One       Date:  2013-02-04       Impact factor: 3.240

10.  Metalloproteinase regulation improves in vitro generation of efficacious platelets from mouse embryonic stem cells.

Authors:  Hidekazu Nishikii; Koji Eto; Noriko Tamura; Koichi Hattori; Beate Heissig; Taisuke Kanaji; Akira Sawaguchi; Shinya Goto; Jerry Ware; Hiromitsu Nakauchi
Journal:  J Exp Med       Date:  2008-07-28       Impact factor: 14.307
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  18 in total

1.  Innovation in the field of thrombocytopenias: achievements since the beginning of the century and promises for the future.

Authors:  Carlo L Balduini; Patrizia Noris
Journal:  Haematologica       Date:  2016-01       Impact factor: 9.941

2.  Nfe2 is dispensable for early but required for adult thrombocyte formation and function in zebrafish.

Authors:  Megan S Rost; Ilya Shestopalov; Yang Liu; Andy H Vo; Catherine E Richter; Sylvia M Emly; Francesca G Barrett; David L Stachura; Michael Holinstat; Leonard I Zon; Jordan A Shavit
Journal:  Blood Adv       Date:  2018-12-11

Review 3.  Towards the Manufacture of Megakaryocytes and Platelets for Clinical Application.

Authors:  Anja Baigger; Rainer Blasczyk; Constanca Figueiredo
Journal:  Transfus Med Hemother       Date:  2017-05-23       Impact factor: 3.747

4.  Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis.

Authors:  Linda M Polfus; Rajiv K Khajuria; Ursula M Schick; Nathan Pankratz; Raha Pazoki; Jennifer A Brody; Ming-Huei Chen; Paul L Auer; James S Floyd; Jie Huang; Leslie Lange; Frank J A van Rooij; Richard A Gibbs; Ginger Metcalf; Donna Muzny; Narayanan Veeraraghavan; Klaudia Walter; Lu Chen; Lisa Yanek; Lewis C Becker; Gina M Peloso; Aoi Wakabayashi; Mart Kals; Andres Metspalu; Tõnu Esko; Keolu Fox; Robert Wallace; Nora Franceschini; Nena Matijevic; Kenneth M Rice; Traci M Bartz; Leo-Pekka Lyytikäinen; Mika Kähönen; Terho Lehtimäki; Olli T Raitakari; Ruifang Li-Gao; Dennis O Mook-Kanamori; Guillaume Lettre; Cornelia M van Duijn; Oscar H Franco; Stephen S Rich; Fernando Rivadeneira; Albert Hofman; André G Uitterlinden; James G Wilson; Bruce M Psaty; Nicole Soranzo; Abbas Dehghan; Eric Boerwinkle; Xiaoling Zhang; Andrew D Johnson; Christopher J O'Donnell; Jill M Johnsen; Alexander P Reiner; Santhi K Ganesh; Vijay G Sankaran
Journal:  Am J Hum Genet       Date:  2016-08-04       Impact factor: 11.025

5.  Label free monitoring of megakaryocytic development and proplatelet formation in vitro.

Authors:  Dimitra Pouli; Lorenzo Tozzi; Carlo A Alonzo; Zhiyi Liu; David L Kaplan; Alessandra Balduini; Irene Georgakoudi
Journal:  Biomed Opt Express       Date:  2017-09-27       Impact factor: 3.732

Review 6.  Platelet bioreactor: accelerated evolution of design and manufacture.

Authors:  Jonathan N Thon; Brad J Dykstra; Lea M Beaulieu
Journal:  Platelets       Date:  2017-01-23       Impact factor: 3.862

7.  Identifying and enriching platelet-producing human stem cell-derived megakaryocytes using factor V uptake.

Authors:  Xiuli Sim; Danuta Jarocha; Vincent Hayes; Hayley A Hanby; Michael S Marks; Rodney M Camire; Deborah L French; Mortimer Poncz; Paul Gadue
Journal:  Blood       Date:  2017-04-28       Impact factor: 22.113

8.  Generation of HLA-Universal iPSC-Derived Megakaryocytes and Platelets for Survival Under Refractoriness Conditions.

Authors:  Ann-Kathrin Börger; Dorothee Eicke; Christina Wolf; Christiane Gras; Susanne Aufderbeck; Kai Schulze; Lena Engels; Britta Eiz-Vesper; Axel Schambach; Carlos A Guzman; Nico Lachmann; Thomas Moritz; Ulrich Martin; Rainer Blasczyk; Constança Figueiredo
Journal:  Mol Med       Date:  2016-05-16       Impact factor: 6.354

Review 9.  The Opportunities and Challenges regarding Induced Platelets from Human Pluripotent Stem Cells.

Authors:  Meng-Xue Xu; Li-Ping Liu; Yu-Mei Li; Yun-Wen Zheng
Journal:  Stem Cells Int       Date:  2021-05-01       Impact factor: 5.443

Review 10.  Process analysis of pluripotent stem cell differentiation to megakaryocytes to make platelets applying European GMP.

Authors:  Moyra Lawrence; Amanda Evans; Thomas Moreau; Marta Bagnati; Matthew Smart; Enas Hassan; Jahid Hasan; Monica Pianella; Julie Kerby; Cedric Ghevaert
Journal:  NPJ Regen Med       Date:  2021-05-26
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