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Literature DB >> 26148656

Hepatitis viruses exploitation of host DNA methyltransferases functions.

Valerio Pazienza¹, Concetta Panebianco², Angelo Andriulli².

Abstract

Hepatitis B virus (HBV), hepatitis C virus (HCV) and Delta (HDV) infections are a global health burden. With different routes of infection and biology, HBV, HCV and HDV are capable to induce liver cirrhosis and cancer by impinging on epigenetic mechanisms altering host cell's pathways. In the present manuscript, we reviewed the published studies taking into account the relationship between the hepatitis viruses and the DNA methyltransferases proteins.

Entities: Disease Species

Keywords: DNMTs; Epigenetics; Hepatitis viruses; Interferon

Mesh：

Substances：
Methyltransferases

Year: 2015 PMID： 26148656 DOI： 10.1007/s10238-015-0372-3

Source DB: PubMed Journal: Clin Exp Med ISSN： 1591-8890 Impact factor: 3.984

116 in total

Review 1. Hepatocellular carcinoma: present status and future prospects.

Authors: Josep M Llovet; Michel Beaugrand
Journal: J Hepatol Date: 2003 Impact factor: 25.083

Review 2. The host immune response may be responsible for selection of envelope and precore/core variants of HBV.

Authors: H C Thomas; W F Carman
Journal: Prog Liver Dis Date: 1992

3. Dnmt3L antagonizes DNA methylation at bivalent promoters and favors DNA methylation at gene bodies in ESCs.

Authors: Francesco Neri; Anna Krepelova; Danny Incarnato; Mara Maldotti; Caterina Parlato; Federico Galvagni; Filomena Matarese; Hendrik G Stunnenberg; Salvatore Oliviero
Journal: Cell Date: 2013-09-26 Impact factor: 41.582

4. Aberrant epigenetic modifications in hepatocarcinogenesis induced by hepatitis B virus X protein.

Authors: In Young Park; Bo Hwa Sohn; Eunsil Yu; Dong Jin Suh; Young-Hwa Chung; Je-Ho Lee; Stefan J Surzycki; Young Ik Lee
Journal: Gastroenterology Date: 2007-01-25 Impact factor: 22.682

5. Epigenetic suppression of the TGF-beta pathway revealed by transcriptome profiling in ovarian cancer.

Authors: Noriomi Matsumura; Zhiqing Huang; Seiichi Mori; Tsukasa Baba; Shingo Fujii; Ikuo Konishi; Edwin S Iversen; Andrew Berchuck; Susan K Murphy
Journal: Genome Res Date: 2010-12-14 Impact factor: 9.043

Review 6. CpG island methylation in precursors of gastrointestinal malignancies.

Authors: Annie On On Chan; Asif Rashid
Journal: Curr Mol Med Date: 2006-06 Impact factor: 2.222

7. In vitro antiviral activity of SCH446211 (SCH6), a novel inhibitor of the hepatitis C virus NS3 serine protease.

Authors: Rong Liu; Karim Abid; John Pichardo; Valerio Pazienza; Paul Ingravallo; Rong Kong; Sony Agrawal; Stephane Bogen; Anil Saksena; Kuo-Chi Cheng; Andrew Prongay; F George Njoroge; Bahige M Baroudy; Francesco Negro
Journal: J Antimicrob Chemother Date: 2006-12-05 Impact factor: 5.790

Hepatitis viruses exploitation of host DNA methyltransferases functions.

Review 1. Hepatocellular carcinoma: present status and future prospects.

Review 2. The host immune response may be responsible for selection of envelope and precore/core variants of HBV.

3. Dnmt3L antagonizes DNA methylation at bivalent promoters and favors DNA methylation at gene bodies in ESCs.

4. Aberrant epigenetic modifications in hepatocarcinogenesis induced by hepatitis B virus X protein.

5. Epigenetic suppression of the TGF-beta pathway revealed by transcriptome profiling in ovarian cancer.

Review 6. CpG island methylation in precursors of gastrointestinal malignancies.

7. In vitro antiviral activity of SCH446211 (SCH6), a novel inhibitor of the hepatitis C virus NS3 serine protease.

Review 8. Cytosine methylation and the ecology of intragenomic parasites.

9. Surveillance for acute viral hepatitis--United States, 2006.

10. Methylation profile of single hepatocytes derived from hepatitis B virus-related hepatocellular carcinoma.

Review 1. DNA Methyltransferases: From Evolution to Clinical Applications.

2. Upregulation of DARS2 by HBV promotes hepatocarcinogenesis through the miR-30e-5p/MAPK/NFAT5 pathway.