Literature DB >> 26147085

Multifunctional hybrid-carbon nanotubes: new horizon in drug delivery and targeting.

Neelesh Kumar Mehra1, Narendra Kumar Jain1.   

Abstract

Carbon nanotubes (CNTs) have emerged as an intriguing nanotechnological tool for numerous biomedical applications including biocompatible modules for the bioactives delivery ascribed to their unique properties, such as greater loading efficiency, biocompatibility, non-immunogenicity, high surface area and photoluminescence, that make them ideal candidate in pharmaceutical and biomedical science. The design of multifunctional hybrid-CNTs for drug delivery and targeting may differ from the conventional drug delivery system. The conventional nanocarriers have few limitations, such as inappropriate availability of surface-chemical functional groups for conjugation, low entrapment/loading efficiency as well as stability as per ICH guidelines with generally regarded as safe (GRAS) prominences. The multifunctional hybrid-CNTs will sparked and open a new door for researchers, scientist of the pharmaceutical and biomedical arena. This review summarizes the vivid aspects of CNTs like characterization, supramolecular chemistry of CNTs-dendrimer, CNTs-nanoparticles, CNTs-quantum dots conjugate for delivery of bioactives, not discussed so far.

Entities:  

Keywords:  Carbon nanotubes; conjugation; dendrimers; multifunctional; quantum dots; supramolecular chemistry

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Substances:

Year:  2015        PMID: 26147085     DOI: 10.3109/1061186X.2015.1055571

Source DB:  PubMed          Journal:  J Drug Target        ISSN: 1026-7158            Impact factor:   5.121


  4 in total

1.  Raman spectrum spectral imaging revealing the molecular mechanism of Berberine-induced Jurkat cell apoptosis and the receptor-mediated Berberine delivery system.

Authors:  Ping Tang; Wendai Cheng; Xuanmeng He; Qinnan Zhang; Jing Zhong; Xiaoxu Lu; Shengde Liu; Liyun Zhong
Journal:  Biomed Opt Express       Date:  2019-03-04       Impact factor: 3.732

2.  Development and Characterization of the Paclitaxel loaded Riboflavin and Thiamine Conjugated Carbon Nanotubes for Cancer Treatment.

Authors:  Swati Singh; Neelesh Kumar Mehra; N K Jain
Journal:  Pharm Res       Date:  2016-04-18       Impact factor: 4.200

Review 3.  Surface Modified Multifunctional and Stimuli Responsive Nanoparticles for Drug Targeting: Current Status and Uses.

Authors:  Panoraia I Siafaka; Neslihan Üstündağ Okur; Evangelos Karavas; Dimitrios N Bikiaris
Journal:  Int J Mol Sci       Date:  2016-08-31       Impact factor: 5.923

Review 4.  Molecular Consortia-Various Structural and Synthetic Concepts for More Effective Therapeutics Synthesis.

Authors:  Anna Pawełczyk; Katarzyna Sowa-Kasprzak; Dorota Olender; Lucjusz Zaprutko
Journal:  Int J Mol Sci       Date:  2018-04-06       Impact factor: 5.923

  4 in total

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