Tao Liu1, Jie Xie1, Fan Yang1, Jia-jun Chen1, Zhan-fei Li1, Cheng-la Yi1, Wei Gao1, Xiang-jun Bai2. 1. Department of Traumatic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430034, China. 2. Department of Traumatic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430034, China. Electronic address: baixiangjun@hotmail.com.
Abstract
BACKGROUND: This study aims to assess the influence of sex on outcomes among trauma patients, including injury severity, medical resource utility, complications, and mortality. METHODS: A systematic review of the literature was conducted by internet search. Data were extracted from selected studies and analyzed using Stata to compare outcomes between male and female injured patients. RESULTS: Eventually, 19 studies met our inclusion criteria with 100,566 men and 39,762 women. Pooled data revealed that male sex was associated with increased risk of mortality, hospital length of stay, and higher incidence of complications. No difference was detected in injury severity between male and female patients. CONCLUSION: Evidence of this meta-analysis strongly supports the sex dimorphism in the prognosis of trauma patients and further work should be done to decipher potential mechanism.
BACKGROUND: This study aims to assess the influence of sex on outcomes among traumapatients, including injury severity, medical resource utility, complications, and mortality. METHODS: A systematic review of the literature was conducted by internet search. Data were extracted from selected studies and analyzed using Stata to compare outcomes between male and female injured patients. RESULTS: Eventually, 19 studies met our inclusion criteria with 100,566 men and 39,762 women. Pooled data revealed that male sex was associated with increased risk of mortality, hospital length of stay, and higher incidence of complications. No difference was detected in injury severity between male and female patients. CONCLUSION: Evidence of this meta-analysis strongly supports the sex dimorphism in the prognosis of traumapatients and further work should be done to decipher potential mechanism.
Authors: Felicia N Williams; Paula D Strassle; Laquanda Knowlin; Sonia Napravnik; David van Duin; Anthony Charles; Rabia Nizamani; Samuel W Jones; Bruce A Cairns Journal: World J Surg Date: 2019-12 Impact factor: 3.352
Authors: Eileen P Scully; Jenna Haverfield; Rebecca L Ursin; Cara Tannenbaum; Sabra L Klein Journal: Nat Rev Immunol Date: 2020-06-11 Impact factor: 108.555