Literature DB >> 26145162

Synthesis of 3-chloro-6-((4-(di-tert-butyl[(18)F]fluorosilyl)-benzyl)oxy)-1,2,4,5-tetrazine ([(18)F]SiFA-OTz) for rapid tetrazine-based (18)F-radiolabeling.

Jun Zhu1, Stephen Li, Carmen Wängler, Björn Wängler, R Bruce Lennox, Ralf Schirrmacher.   

Abstract

An efficient method to prepare the (18)F-labeled tetrazine-derivative [(18)F]-SiFA-OTz for bioorthogonal radiochemistry was developed. [(18)F]-SiFA-OTz can be synthesized with a radiochemical yield of 78 ± 5% within 25 min and can quantitatively react with a model strained dienophile, trans-cyclooctenol.

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Year:  2015        PMID： 26145162     DOI： 10.1039/c5cc03623b

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  12 in total

Review 1.  18 F-Labeling of Sensitive Biomolecules for Positron Emission Tomography.

Authors:  Hema S Krishnan; Longle Ma; Neil Vasdev; Steven H Liang
Journal:  Chemistry       Date:  2017-09-01       Impact factor: 5.236

Review 2.  Click Chemistry and Radiochemistry: The First 10 Years.

Authors:  Jan-Philip Meyer; Pierre Adumeau; Jason S Lewis; Brian M Zeglis
Journal:  Bioconjug Chem       Date:  2016-11-22       Impact factor: 4.774

Review 3.  Recent Advances in the Development of Tetrazine Ligation Tools for Pretargeted Nuclear Imaging.

Authors:  Rocío García-Vázquez; Umberto Maria Battisti; Matthias M Herth
Journal:  Pharmaceuticals (Basel)       Date:  2022-05-30

4.  A New Highly Reactive and Low Lipophilicity Fluorine-18 Labeled Tetrazine Derivative for Pretargeted PET Imaging.

Authors:  Outi Keinänen; Xiang-Guo Li; Naveen K Chenna; Dave Lumen; Jennifer Ott; Carla F M Molthoff; Mirkka Sarparanta; Kerttuli Helariutta; Tapani Vuorinen; Albert D Windhorst; Anu J Airaksinen
Journal:  ACS Med Chem Lett       Date:  2015-12-10       Impact factor: 4.345

5.  Conformationally Strained trans-Cyclooctene (sTCO) Enables the Rapid Construction of (18)F-PET Probes via Tetrazine Ligation.

Authors:  Mengzhe Wang; Dennis Svatunek; Katarina Rohlfing; Yu Liu; Hui Wang; Ben Giglio; Hong Yuan; Zhanghong Wu; Zibo Li; Joseph Fox
Journal:  Theranostics       Date:  2016-04-12       Impact factor: 11.556

6.  (18)F-Based Pretargeted PET Imaging Based on Bioorthogonal Diels-Alder Click Chemistry.

Authors:  Jan-Philip Meyer; Jacob L Houghton; Paul Kozlowski; Dalya Abdel-Atti; Thomas Reiner; Naga Vara Kishore Pillarsetty; Wolfgang W Scholz; Brian M Zeglis; Jason S Lewis
Journal:  Bioconjug Chem       Date:  2015-10-28       Impact factor: 4.774

7.  A Pretargeted Approach for the Multimodal PET/NIRF Imaging of Colorectal Cancer.

Authors:  Pierre Adumeau; Kathryn E Carnazza; Christian Brand; Sean D Carlin; Thomas Reiner; Brian J Agnew; Jason S Lewis; Brian M Zeglis
Journal:  Theranostics       Date:  2016-09-28       Impact factor: 11.556

8.  Efficient low-cost preparation of trans-cyclooctenes using a simplified flow setup for photoisomerization.

Authors:  Dennis Svatunek; Christoph Denk; Veronika Rosecker; Barbara Sohr; Christian Hametner; Günter Allmaier; Johannes Fröhlich; Hannes Mikula
Journal:  Monatsh Chem       Date:  2016-02-22       Impact factor: 1.451

Review 9.  Recent Advances in Bioorthogonal Click Chemistry for Efficient Synthesis of Radiotracers and Radiopharmaceuticals.

Authors:  Sajid Mushtaq; Seong-Jae Yun; Jongho Jeon
Journal:  Molecules       Date:  2019-10-02       Impact factor: 4.411

10.  Evaluation of Organo [18F]Fluorosilicon Tetrazine as a Prosthetic Group for the Synthesis of PET Radiotracers.

Authors:  Sofia Otaru; Surachet Imlimthan; Mirkka Sarparanta; Kerttuli Helariutta; Kristiina Wähälä; Anu J Airaksinen
Journal:  Molecules       Date:  2020-03-07       Impact factor: 4.411
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