| Literature DB >> 2614436 |
C Chiron1, C Raynaud, N Tzourio, C Diebler, O Dulac, M Zilbovicius, A Syrota.
Abstract
Regional cerebral blood flow (rCBF) was studied using SPECT (single photon emission computed tomography) with 133-Xenon in 13 patients with confirmed Sturge-Weber disease, aged 9 months to 18 years. CT scan, performed at the same time, showed evident cerebral angioma in 10 but not in three. A marked hypoperfused area was found in all patients, ranging from -32% to -72% and of the same location as the CT signs. The hypoperfusion seems to result from post ictal phenomenon as well as from chronic ischaemia. SPECT imaging is therefore a sensitive method for visualising intracranial angioma in Sturge-Weber disease and it provides an aid for diagnosis when a CT scan is not reliable.Entities:
Mesh:
Year: 1989 PMID: 2614436 PMCID: PMC1031599 DOI: 10.1136/jnnp.52.12.1402
Source DB: PubMed Journal: J Neurol Neurosurg Psychiatry ISSN: 0022-3050 Impact factor: 10.154