Literature DB >> 26142391

Warfarin-related recurrent knee haemarthrosis treated with arterial embolisation and intra-articular injection of tranexamic acid.

Yasuo Kunugiza1, Yoshiharu Nakamura1, Koji Mikami2, Shozo Suzuki1.   

Abstract

Haemarthrosis is an uncommon complication of anticoagulation therapy. Tranexamic acid (TXA) has a high clinical value for the treatment of bleeding due to fibrinolysis. We describe a case of a 61-year-old woman with a mechanical heart valve who presented with warfarin-related recurrent haemarthrosis of her right knee, which recurred after transarterial embolisation. Intra-articular injection of TXA led to a cessation of haemarthrosis without any adverse event for 1 year. Intra-articular injection of TXA may be an effective treatment for warfarin-related haemarthrosis. 2015 BMJ Publishing Group Ltd.

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Year:  2015        PMID： 26142391      PMCID： PMC4493170          DOI： 10.1136/bcr-2015-210203

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN： 1757-790X


  18 in total

1.  Correlation between different intensities of anti-vitamin K treatment and coagulation parameters.

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Journal:  Thromb Res       Date:  2000-06-15       Impact factor: 3.944

Review 2.  Cartilage damage in the haemophilic joints: pathophysiology, diagnosis and management.

Authors:  E Carlos Rodriguez-Merchan
Journal:  Blood Coagul Fibrinolysis       Date:  2012-04       Impact factor: 1.276

3.  Low risk of thromboembolic complications with tranexamic acid after primary total hip and knee arthroplasty.

Authors:  Blake P Gillette; Lori J DeSimone; Robert T Trousdale; Mark W Pagnano; Rafael J Sierra
Journal:  Clin Orthop Relat Res       Date:  2013-01       Impact factor: 4.176

4.  Role of urokinase and tissue activator in sustaining bleeding and the management thereof with EACA and AMCA.

Authors:  L Andersson; I M Nilsoon; S Colleen; B Granstrand; B Melander
Journal:  Ann N Y Acad Sci       Date:  1968-06-28       Impact factor: 5.691

Review 5.  Clinical pharmacology of tranexamic acid.

Authors:  B Astedt
Journal:  Scand J Gastroenterol Suppl       Date:  1987

6.  Effect of warfarin treatment on thrombin activatable fibrinolysis inhibitor (TAFI) activation and TAFI-mediated inhibition of fibrinolysis.

Authors:  F Incampo; C Carrieri; R Galasso; F A Scaraggi; F Di Serio; B Woodhams; N Semeraro; M Colucci
Journal:  J Thromb Haemost       Date:  2013-02       Impact factor: 5.824

7.  Tranexamic acid mouthwash versus autologous fibrin glue in patients taking warfarin undergoing dental extractions: a randomized prospective clinical study.

Authors:  Glen Carter; Alastair Goss; John Lloyd; Ric Tocchetti
Journal:  J Oral Maxillofac Surg       Date:  2003-12       Impact factor: 1.895

8.  Suppression of hemostatic system activation by oral anticoagulants in the blood of patients with thrombotic diatheses.

Authors:  E M Conway; K A Bauer; S Barzegar; R D Rosenberg
Journal:  J Clin Invest       Date:  1987-12       Impact factor: 14.808

9.  Repeat-dose intravenous tranexamic acid further decreases blood loss in total knee arthroplasty.

Authors:  Takao Iwai; Shigeyoshi Tsuji; Tetsuya Tomita; Kazuomi Sugamoto; Yoshikawa Hideki; Masayuki Hamada
Journal:  Int Orthop       Date:  2013-02-01       Impact factor: 3.075

Review 10.  The effect of cooling on coagulation and haemostasis: should "Ice" be part of treatment of acute haemarthrosis in haemophilia?

Authors:  A L Forsyth; N Zourikian; L A Valentino; G E Rivard
Journal:  Haemophilia       Date:  2012-08-23       Impact factor: 4.287
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  2 in total

1.  Management of Haemarthrosis in Patients On Oral Anticoagulants.

Authors:  James Dalrymple; Andrew Davies; Alexandra Biggs; Shahil Rajcoomar; Ian Gill
Journal:  Geriatr Orthop Surg Rehabil       Date:  2022-05-11

2.  Tranexamic acid toxicity in human periarticular tissues.

Authors:  M McLean; K McCall; I D M Smith; M Blyth; S M Kitson; L A N Crowe; W J Leach; B P Rooney; S J Spencer; M Mullen; J L Campton; I B McInnes; M Akbar; N L Millar
Journal:  Bone Joint Res       Date:  2019-02-02       Impact factor: 5.853
  2 in total

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