Literature DB >> 26142086

Hard calcified intrasellar schwannoma mimicking pituitary adenoma: a case report and review of the literature.

Guive Sharifi1, Mehrdad Hosseinzadeh Bakhtevari2, Mohsen Alghasi3, Masood Saberi4, Mahmood Dehghan1, Farahnaz Bidari5, Omidvar Rezaei1.   

Abstract

BACKGROUND: Intrasellar location of schwannoma is extremely rare, although intracranial schwannomas are common in the central nervous system. The aim of the present study is to describe a calcified intrasellar schwannoma case.
MATERIALS AND METHODS: We represent a 45-year-old woman who had suffered from headaches; right side facial pain and visual disturbance which had worsen during the last week prior to admission. Physical examinations were normal except for the bitemporal visual field hemianopia which match with perimetry examination. MRI demonstrated an unusual seemingly calcified mass lesion in the sellar region which was mimicking pituitary macro adenoma. RESULT: Total resection of the tumor achieved through endoscopic transnasal transsphenoidal approach by extracapsular dissection and pathologic examination of the tumor revealed calcified schwannoma.
CONCLUSION: The differential diagnoses of sellar and suprasellar lesions include pituitary adenomas, craniopharyngiomas, meningiomas, and many others. However, schwannoma is not usually included, because the occurrence of schwannoma in the sellar or suprasellar region is extremely rare. Only few cases of intrasellar schwannomas have been reported in the literature, all of which presented a suprasellar extension similar to that of our case. Fascinating surgical point is managing very firm tumor through transsphenoidal corridor which we handle it by very sharp, debulking and extracapsular removal.
Copyright © 2015 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Calcified; Pituitary; Schwannoma; Sellar

Mesh:

Year:  2015        PMID: 26142086     DOI: 10.1016/j.clineuro.2015.06.001

Source DB:  PubMed          Journal:  Clin Neurol Neurosurg        ISSN: 0303-8467            Impact factor:   1.876


  4 in total

1.  [The 2017 WHO classification of pituitary tumors].

Authors:  Wolfgang Saeger
Journal:  Pathologe       Date:  2021-04-20       Impact factor: 1.011

Review 2.  Intra-Suprasellar Schwannoma Presumably Originating from the Internal Carotid Artery Wall : Case Report and Review of the Literature.

Authors:  Sohi Bae; Sung Soo Ahn; Jong Hee Chang; Se Hoon Kim
Journal:  Clin Neuroradiol       Date:  2017-06-02       Impact factor: 3.649

3.  TFF3 knockout in human pituitary adenoma cell HP75 facilitates cell apoptosis via mitochondrial pathway.

Authors:  Feng Gao; Suxia Pan; Bing Liu; Huanzhi Zhang
Journal:  Int J Clin Exp Pathol       Date:  2015-11-01

Review 4.  Schwannoma in Sellar Region Mimics Invasive Pituitary Macroadenoma: Literature Review With One Case Report.

Authors:  Xiangyi Kong; Huanwen Wu; Wenbin Ma; Yongning Li; Yi Yang; Bing Xing; Junji Wei; Yong Yao; Jun Gao; Wei Lian; Zhiqin Xu; Wanchen Dou; Zuyuan Ren; Changbao Su; Renzhi Wang
Journal:  Medicine (Baltimore)       Date:  2016-03       Impact factor: 1.889

  4 in total

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