Literature DB >> 26141798

Clinical application of companion diagnostics.

Jan Trøst Jørgensen1.   

Abstract

Optimally, any prescription should rely on an in-depth understanding of the disease biology and the mechanism of action of the drug. However, despite the hype about precision medicine in recent years, the prescription of most drugs is still, except for a few anticancer drugs, largely based on 'trial and error' and not on solid pharmacogenomic biomarker data.
Copyright © 2015 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  companion diagnostics; drug efficacy; oncology; pharmacogenetics; pharmacotherapy; precision medicine

Mesh：

Substances：

Year:  2015        PMID： 26141798     DOI： 10.1016/j.molmed.2015.05.003

Source DB:  PubMed          Journal:  Trends Mol Med        ISSN： 1471-4914            Impact factor:   11.951


  9 in total

Review 1.  Companion diagnostics-a tool to improve pharmacotherapy.

Authors:  Jan Trøst Jørgensen; Maria Hersom
Journal:  Ann Transl Med       Date:  2016-12

2.  A Precision Medicine Model for Targeted NSAID Therapy in Alzheimer's Disease.

Authors:  Sid E O'Bryant; Fan Zhang; Leigh A Johnson; James Hall; Melissa Edwards; Paula Grammas; Esther Oh; Constantine G Lyketsos; Robert A Rissman
Journal:  J Alzheimers Dis       Date:  2018       Impact factor: 4.472

3.  Twenty Years with Personalized Medicine: Past, Present, and Future of Individualized Pharmacotherapy.

Authors:  Jan Trøst Jørgensen
Journal:  Oncologist       Date:  2019-04-02

4.  Impact of Availability of Companion Diagnostics on the Clinical Development of Anticancer Drugs.

Authors:  Ariadna Tibau; Laura Díez-González; Beatriz Navarro; Eva M Galán-Moya; Arnoud J Templeton; Bostjan Seruga; Atanasio Pandiella; Eitan Amir; Alberto Ocana
Journal:  Mol Diagn Ther       Date:  2017-06       Impact factor: 4.074

5.  Effective quality management practices in routine clinical next-generation sequencing.

Authors:  Francine B de Abreu; Jason D Peterson; Christopher I Amos; Wendy A Wells; Gregory J Tsongalis
Journal:  Clin Chem Lab Med       Date:  2016-05       Impact factor: 3.694

6.  A Precision Medicine Approach to Treating Alzheimer's Disease Using Rosiglitazone Therapy: A Biomarker Analysis of the REFLECT Trials.

Authors:  Sid E O'Bryant; Fan Zhang; Melissa Petersen; Leigh Johnson; James Hall; Robert A Rissman
Journal:  J Alzheimers Dis       Date:  2021       Impact factor: 4.472

7.  Proteomic profiles of prevalent mild cognitive impairment and Alzheimer's disease among adults with Down syndrome.

Authors:  Melissa Petersen; Fan Zhang; Sharon J Krinsky-McHale; Wayne Silverman; Joseph H Lee; Deborah Pang; James Hall; Nicole Schupf; Sid E O'Bryant
Journal:  Alzheimers Dement (Amst)       Date:  2020-04-17

8.  SEPROGADIC - serum protein-based gastric cancer prediction model for prognosis and selection of proper adjuvant therapy.

Authors:  Hee-Sung Ahn; Tae Sung Sohn; Mi Jeong Kim; Byoung Kyu Cho; Su Mi Kim; Seung Tae Kim; Eugene C Yi; Cheolju Lee
Journal:  Sci Rep       Date:  2018-11-15       Impact factor: 4.379

9.  Proteomic profiles of incident mild cognitive impairment and Alzheimer's disease among adults with Down syndrome.

Authors:  Sid E O'Bryant; Fan Zhang; Wayne Silverman; Joseph H Lee; Sharon J Krinsky-McHale; Deborah Pang; James Hall; Nicole Schupf
Journal:  Alzheimers Dement (Amst)       Date:  2020-05-21
  9 in total

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