Literature DB >> 26140724

Ion Channels in the Heart.

Daniel C Bartos1, Eleonora Grandi1, Crystal M Ripplinger1.   

Abstract

Optimal cardiac function depends on proper timing of excitation and contraction in various regions of the heart, as well as on appropriate heart rate. This is accomplished via specialized electrical properties of various components of the system, including the sinoatrial node, atria, atrioventricular node, His-Purkinje system, and ventricles. Here we review the major regionally determined electrical properties of these cardiac regions and present the available data regarding the molecular and ionic bases of regional cardiac function and dysfunction. Understanding these differences is of fundamental importance for the investigation of arrhythmia mechanisms and pharmacotherapy.
© 2015 American Physiological Society.

Entities:  

Mesh：

Substances：

Year:  2015        PMID： 26140724      PMCID： PMC4516287          DOI： 10.1002/cphy.c140069

Source DB:  PubMed          Journal:  Compr Physiol        ISSN： 2040-4603            Impact factor:   9.090


  587 in total

1.  Reopening of L-type calcium channels in human ventricular myocytes during applied epicardial action potentials.

Authors:  L Fülöp; T Bányász; J Magyar; N Szentandrássy; A Varró; P P Nánási
Journal:  Acta Physiol Scand       Date:  2004-01

2.  Ionic remodeling of sinoatrial node cells by heart failure.

Authors:  Arie O Verkerk; Ronald Wilders; Ruben Coronel; Jan H Ravesloot; E Etienne Verheijck
Journal:  Circulation       Date:  2003-07-28       Impact factor: 29.690

3.  Correlation between electrical activity and the size of rabbit sino-atrial node cells.

Authors:  H Honjo; M R Boyett; I Kodama; J Toyama
Journal:  J Physiol       Date:  1996-11-01       Impact factor: 5.182

4.  Ion channel remodeling is related to intraoperative atrial effective refractory periods in patients with paroxysmal and persistent atrial fibrillation.

Authors:  B J Brundel; I C Van Gelder ; R H Henning; R G Tieleman; A E Tuinenburg; M Wietses; J G Grandjean; W H Van Gilst ; H J Crijns
Journal:  Circulation       Date:  2001-02-06       Impact factor: 29.690

Review 5.  Atrial fibrillation and congestive heart failure: specific considerations at the intersection of two common and important cardiac disease sets.

Authors:  Joachim R Ehrlich; Stanley Nattel; Stefan H Hohnloser
Journal:  J Cardiovasc Electrophysiol       Date:  2002-04

6.  Comparison of cloned Kir2 channels with native inward rectifier K+ channels from guinea-pig cardiomyocytes.

Authors:  G X Liu; C Derst; G Schlichthörl; S Heinen; G Seebohm; A Brüggemann; W Kummer; R W Veh; J Daut; R Preisig-Müller
Journal:  J Physiol       Date:  2001-04-01       Impact factor: 5.182

7.  In vitro molecular interactions and distribution of KCNE family with KCNQ1 in the human heart.

Authors:  Saïd Bendahhou; Céline Marionneau; Karinne Haurogne; Marie-Madeleine Larroque; Renaud Derand; Viktoria Szuts; Denis Escande; Sophie Demolombe; Jacques Barhanin
Journal:  Cardiovasc Res       Date:  2005-03-21       Impact factor: 10.787

8.  Mutation in nuclear pore component NUP155 leads to atrial fibrillation and early sudden cardiac death.

Authors:  Xianqin Zhang; Shenghan Chen; Shin Yoo; Susmita Chakrabarti; Teng Zhang; Tie Ke; Carlos Oberti; Sandro L Yong; Fang Fang; Lin Li; Roberto de la Fuente; Lejin Wang; Qiuyun Chen; Qing Kenneth Wang
Journal:  Cell       Date:  2008-12-12       Impact factor: 41.582

9.  Heart failure causes cholinergic transdifferentiation of cardiac sympathetic nerves via gp130-signaling cytokines in rodents.

Authors:  Hideaki Kanazawa; Masaki Ieda; Kensuke Kimura; Takahide Arai; Haruko Kawaguchi-Manabe; Tomohiro Matsuhashi; Jin Endo; Motoaki Sano; Takashi Kawakami; Tokuhiro Kimura; Toshiaki Monkawa; Matsuhiko Hayashi; Akio Iwanami; Hideyuki Okano; Yasunori Okada; Hatsue Ishibashi-Ueda; Satoshi Ogawa; Keiichi Fukuda
Journal:  J Clin Invest       Date:  2010-01-04       Impact factor: 14.808

10.  Variations of autonomic tone preceding onset of atrial fibrillation after coronary artery bypass grafting.

Authors:  C Dimmer; R Tavernier; N Gjorgov; G Van Nooten; D L Clement; L Jordaens
Journal:  Am J Cardiol       Date:  1998-07-01       Impact factor: 2.778
View more
  54 in total

Review 1.  Serine/Threonine Phosphatases in Atrial Fibrillation.

Authors:  Jordi Heijman; Shokoufeh Ghezelbash; Xander H T Wehrens; Dobromir Dobrev
Journal:  J Mol Cell Cardiol       Date:  2017-01-07       Impact factor: 5.000

Review 2.  In vitro models of the cardiac microenvironment to study myocyte and non-myocyte crosstalk: bioinspired approaches beyond the polystyrene dish.

Authors:  Celinda M Kofron; Ulrike Mende
Journal:  J Physiol       Date:  2017-02-27       Impact factor: 5.182

3.  The best thing since sliced bread? Optical mapping of transverse cardiac slices in the mouse heart.

Authors:  Crystal M Ripplinger
Journal:  J Physiol       Date:  2018-07-21       Impact factor: 5.182

4.  Differences in Left Versus Right Ventricular Electrophysiological Properties in Cardiac Dysfunction and Arrhythmogenesis.

Authors:  Cristina E Molina; Jordi Heijman; Dobromir Dobrev
Journal:  Arrhythm Electrophysiol Rev       Date:  2016-05

5.  Quantitative analysis of the Ca2+ -dependent regulation of delayed rectifier K+ current IKs in rabbit ventricular myocytes.

Authors:  Daniel C Bartos; Stefano Morotti; Kenneth S Ginsburg; Eleonora Grandi; Donald M Bers
Journal:  J Physiol       Date:  2017-03-28       Impact factor: 5.182

Review 6.  Investigational antiarrhythmic agents: promising drugs in early clinical development.

Authors:  Jordi Heijman; Shokoufeh Ghezelbash; Dobromir Dobrev
Journal:  Expert Opin Investig Drugs       Date:  2017-07-20       Impact factor: 6.206

7.  Transcriptomic Profiling of the Developing Cardiac Conduction System at Single-Cell Resolution.

Authors:  William R Goodyer; Benjamin M Beyersdorf; David T Paik; Lei Tian; Guang Li; Jan W Buikema; Orlando Chirikian; Shannon Choi; Sneha Venkatraman; Eliza L Adams; Marc Tessier-Lavigne; Joseph C Wu; Sean M Wu
Journal:  Circ Res       Date:  2019-07-09       Impact factor: 17.367

8.  Inhibition of inwardly rectifying Kir2.x channels by the novel anti-cancer agent gambogic acid depends on both pore block and PIP2 interference.

Authors:  Daniel Scherer; Benedikt Schworm; Claudia Seyler; Panagiotis Xynogalos; Eberhard P Scholz; Dierk Thomas; Hugo A Katus; Edgar Zitron
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2017-04-02       Impact factor: 3.000

Review 9.  Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes as Models for Cardiac Channelopathies: A Primer for Non-Electrophysiologists.

Authors:  Priyanka Garg; Vivek Garg; Rajani Shrestha; Michael C Sanguinetti; Timothy J Kamp; Joseph C Wu
Journal:  Circ Res       Date:  2018-07-06       Impact factor: 17.367

Review 10.  Potassium channels in the heart: structure, function and regulation.

Authors:  Eleonora Grandi; Michael C Sanguinetti; Daniel C Bartos; Donald M Bers; Ye Chen-Izu; Nipavan Chiamvimonvat; Henry M Colecraft; Brian P Delisle; Jordi Heijman; Manuel F Navedo; Sergei Noskov; Catherine Proenza; Jamie I Vandenberg; Vladimir Yarov-Yarovoy
Journal:  J Physiol       Date:  2016-11-13       Impact factor: 5.182
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.