Literature DB >> 26140678

A target-induced three-way G-quadruplex junction for 17β-estradiol monitoring with a naked-eye readout.

Junhua Chen1, Junlin Wen, Guiqin Yang, Shungui Zhou.   

Abstract

A label-free and enzyme-free three-way G-quadruplex junction sensing system for the amplified detection of 17β-estradiol has been constructed by the ingenious coupling of split G-quadruplex DNAzyme with toehold-mediated strand displacement. The biosensor is ultrasensitive, enabling the visual detection of 17β-estradiol concentrations as low as 1 fM without instrumentation.

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Year:  2015        PMID: 26140678     DOI: 10.1039/c5cc04347f

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  2 in total

1.  A label-free and enzyme-free platform with a visible output for constructing versatile logic gates using caged G-quadruplex as the signal transducer.

Authors:  Junhua Chen; Jiafeng Pan; Shu Chen
Journal:  Chem Sci       Date:  2017-10-20       Impact factor: 9.825

2.  Turn-off colorimetric sensor for sequence-specific recognition of single-stranded DNA based upon Y-shaped DNA structure.

Authors:  Hong Zhang; Xintong Li; Fan He; Mingqin Zhao; Liansheng Ling
Journal:  Sci Rep       Date:  2018-08-13       Impact factor: 4.379

  2 in total

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