Literature DB >> 26140339

Efficacy of Zero-Profile Implant in Anterior Fusion to Treat Degenerative Cervical Spine Disease: Comparison with Techniques Using Bone Graft and Anterior Plating.

Han Chang1, Dong-Hoon Baek2, Byung-Wan Choi2.   

Abstract

BACKGROUND: The efficacy of anterior fusion using zero-profile implant (Zero-P) in the surgical treatment of degenerative cervical disease was investigated through radiographic and clinical comparisons with existing treatments using autograft or allograft and anterior plating.
MATERIAL AND METHODS: A total of 130 patients who underwent anterior decompression and fusion for degenerative cervical spine disease with a follow-up of at least 1 year were analyzed retrospectively. The cases were divided into three groups: autograft and plate (38 cases, group A), allograft and plate (44 cases, group B), and Zero-P (48 cases, group C). Maintenance of lordosis, extent of subsidence, and fusion were evaluated radiologically and compared among preoperative, postoperative, and final follow-up time points. In addition, changes in Visual Analog Scale (VAS) and Neurologic Disability Index (NDI) scores and the presence of complications were evaluated for clinical analysis.
RESULTS: Operation time was significantly less in group C (p = 0.007, 0.002). Maintenance of entire and segmental lordosis after surgery was better in groups A and B compared with group C (p = 0.002, 0.001); however, the extent of loss of lordosis from the surgery to the final follow-up did not show any significant differences. Regarding the extent of subsidence, the increase of height between the vertebral bodies after the surgery was 3.10, 2.89, and 2.68 mm in group A, group B, and group C, respectively (p = 0.14), and changed to - 1.27, - 2.41, and - 1.2 mm at the final follow-up (p = 0.012). VAS and NDI scores were improved from 7.2 to 3 and 34 to 12, respectively, but there were no significant differences. Nonunion occurred in two cases in both group B and group C. In terms of clinical complications, two cases of persistent donor site pain were found in group A; one case of persistent dysphagia was found in both group A and group B.
CONCLUSION: Anterior cervical fusion using Zero-P has a shorter operation time and less subsidence compared with conventional surgical techniques. Thus it can be considered a useful technique for the surgical treatment of degenerative cervical disease. Georg Thieme Verlag KG Stuttgart · New York.

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Year:  2015        PMID: 26140339     DOI: 10.1055/s-0034-1389091

Source DB:  PubMed          Journal:  J Neurol Surg A Cent Eur Neurosurg        ISSN: 2193-6315            Impact factor:   1.268


  3 in total

Review 1.  Autograft versus Allograft for Cervical Spinal Fusion: A Systematic Review.

Authors:  Alexander Tuchman; Darrel S Brodke; Jim A Youssef; Hans-Jörg Meisel; Joseph R Dettori; Jong-Beom Park; S Tim Yoon; Jeffrey C Wang
Journal:  Global Spine J       Date:  2017-02-01

Review 2.  Comparison of outcomes between Zero-p implant and anterior cervical plate interbody fusion systems for anterior cervical decompression and fusion: a systematic review and meta-analysis of randomized controlled trials.

Authors:  Tingxin Zhang; Nana Guo; Gang Gao; Hao Liu; Yanhong Li; Feng Gao; Qingxin Zhang; Xiaoyang Tao; Wupeng Yang; Yongjiang Wang
Journal:  J Orthop Surg Res       Date:  2022-01-25       Impact factor: 2.359

3.  Autologous Stem Cells in Cervical Spine Fusion.

Authors:  Patrick C Hsieh; Andrew S Chung; Darrel Brodke; Jong-Beom Park; Andrea C Skelly; Erika D Brodt; Ki Chang; Zorica Buser; Hans Joerg Meisel; S Timothy Yoon; Jeffrey C Wang
Journal:  Global Spine J       Date:  2020-09-23
  3 in total

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