Literature DB >> 26139996

Patient characteristics with high or low blood urea nitrogen in upper gastrointestinal bleeding.

Minoru Tomizawa1, Fuminobu Shinozaki1, Rumiko Hasegawa1, Yoshinori Shirai1, Yasufumi Motoyoshi1, Takao Sugiyama1, Shigenori Yamamoto1, Naoki Ishige1.   

Abstract

AIM: To examine characteristics of patients with blood urea nitrogen (BUN) levels higher and lower than the normal limit.
METHODS: Patient records between April 2011 and March 2014 were analyzed retrospectively. During this time, 3296 patients underwent upper endoscopy. In total, 50 male (69.2 ± 13.2 years) and 26 female (72.3 ± 10.2 years) patients were assessed. Patients were divided into two groups based on BUN levels: higher than the normal limit (21.0 mg/dL) (H) and lower than the normal limit (L). One-way analysis of variance was performed to reveal differences in the variables between the H and L groups. Fisher's exact test was used to compare the percentage of patients with gastric ulcer or gastric cancer in the H and L groups.
RESULTS: White blood cell count was higher in the H group than in the L group (P = 0.0047). Hemoglobin level was lower in the H group than in the L group (P = 0.0307). Glycated hemoglobin was higher in the H group than in the L group (P = 0.0264). The percentage of patients with gastric ulcer was higher in the H group (P = 0.0002). The H group contained no patients with gastric cancer.
CONCLUSION: Patients with BUN ≥ 21 mg/dL might have more severe upper gastrointestinal bleeding.

Entities:  

Keywords:  Blood urea nitrogen; Forrest classification; Hemoglobin; White blood cell count

Mesh:

Substances:

Year:  2015        PMID: 26139996      PMCID: PMC4481445          DOI: 10.3748/wjg.v21.i24.7500

Source DB:  PubMed          Journal:  World J Gastroenterol        ISSN: 1007-9327            Impact factor:   5.742


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