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Literature DB >> 26139589

PLA2-responsive and SPIO-loaded phospholipid micelles.

Qiang Gao¹, Lesan Yan, Michael Chiorazzo, E James Delikatny, Andrew Tsourkas, Zhiliang Cheng.

Abstract

PLA2-responsive and superparamagnetic iron oxide (SPIO) nanoparticle-loaded phospholipid micelles were developed. The release of a phospholipid-conjugated dye from these micelles was triggered due to phospholipid degradation by phospholipase A2. The high relaxivity of the encapsulated SPIO could enable non-invasive magnetic resonance imaging.

Entities: Chemical Disease Gene

Mesh：

Substances：

Year: 2015 PMID： 26139589 PMCID： PMC4506235 DOI： 10.1039/c5cc04540a

Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222

22 in total

1. Group II phospholipase A2 is increased in peritoneal and pleural effusions in patients with various types of cancer.

Authors: T Abe; K Sakamoto; H Kamohara; Y Hirano; N Kuwahara; M Ogawa
Journal: Int J Cancer Date: 1997-06-20 Impact factor: 7.396

2. Circulating levels of secretory type II phospholipase A(2) predict coronary events in patients with coronary artery disease.

Authors: K Kugiyama; Y Ota; K Takazoe; Y Moriyama; H Kawano; Y Miyao; T Sakamoto; H Soejima; H Ogawa; H Doi; S Sugiyama; H Yasue
Journal: Circulation Date: 1999-09-21 Impact factor: 29.690

3. Submicron lipid emulsion as a drug delivery system for nalbuphine and its prodrugs.

Authors: Jhi-Joung Wang; K C Sung; Oliver Yoa-Pu Hu; Chih-Hui Yeh; Jia-You Fang
Journal: J Control Release Date: 2006-07-28 Impact factor: 9.776

4. Inhibition of phospholipase A2 by cis-unsaturated fatty acids: evidence for the binding of fatty acid to enzyme.

Authors: R Raghupathi; R C Franson
Journal: Biochim Biophys Acta Date: 1992-06-22

5. Expression of group IIA secretory phospholipase A2 is elevated in prostatic intraepithelial neoplasia and adenocarcinoma.

Authors: Jiazhong Jiang; Blake Lee Neubauer; Jeremy R Graff; Marcio Chedid; James E Thomas; Neal W Roehm; Shaobo Zhang; George J Eckert; Michael O Koch; John N Eble; Liang Cheng
Journal: Am J Pathol Date: 2002-02 Impact factor: 4.307

Review 6. Micelles from lipid derivatives of water-soluble polymers as delivery systems for poorly soluble drugs.

Authors: Anatoly N Lukyanov; Vladimir P Torchilin
Journal: Adv Drug Deliv Rev Date: 2004-05-07 Impact factor: 15.470

7. Circulating phospholipase A2 activity associated with sepsis and septic shock is indistinguishable from that associated with rheumatoid arthritis.

Authors: J A Green; G M Smith; R Buchta; R Lee; K Y Ho; I A Rajkovic; K F Scott
Journal: Inflammation Date: 1991-10 Impact factor: 4.092

8. Oncogenic action of secreted phospholipase A2 in prostate cancer.

Authors: Paul Sved; Kieran F Scott; Duncan McLeod; Nicholas J C King; Jas Singh; Tania Tsatralis; Blagoy Nikolov; John Boulas; Laxman Nallan; Michael H Gelb; Mila Sajinovic; Garry G Graham; Pamela J Russell; Qihan Dong
Journal: Cancer Res Date: 2004-10-01 Impact factor: 12.701

9. The oral absorption of phospholipid prodrugs: in vivo and in vitro mechanistic investigation of trafficking of a lecithin-valproic acid conjugate following oral administration.

Authors: Arik Dahan; Revital Duvdevani; Israel Shapiro; Anat Elmann; Elena Finkelstein; Amnon Hoffman
Journal: J Control Release Date: 2007-11-07 Impact factor: 9.776

10. Monitoring phospholipase A₂ activity with Gd-encapsulated phospholipid liposomes.

Authors: Zhiliang Cheng; Andrew Tsourkas
Journal: Sci Rep Date: 2014-11-07 Impact factor: 4.379

4 in total

1. Quantum dot cluster (QDC)-loaded phospholipid micelles as a FRET probe for phospholipase A₂ detection.

Authors: Junling Li; Yonghua Zhang; Junjie Ai; Qiang Gao; Honglan Qi; Chengxiao Zhang; Zhiliang Cheng
Journal: RSC Adv Date: 2016-02-01 Impact factor: 3.361

2. Detection and Differentiation of Breast Cancer Sub-Types using a cPLA2α Activatable Fluorophore.

Authors: Michael G Chiorazzo; Hanna Maja Tunset; Anatoliy V Popov; Berit Johansen; Siver Moestue; E James Delikatny
Journal: Sci Rep Date: 2019-04-16 Impact factor: 4.379

3. Phospholipase A₂ inhibitor-loaded micellar nanoparticles attenuate inflammation and mitigate osteoarthritis progression.

Authors: Yulong Wei; Lesan Yan; Lijun Luo; Tao Gui; Bian Jang; Ahmad Amirshaghaghi; Tianyan You; Andrew Tsourkas; Ling Qin; Zhiliang Cheng
Journal: Sci Adv Date: 2021-04-07 Impact factor: 14.136

4. Phospholipase A₂ Inhibitor-Loaded Phospholipid Micelles Abolish Neuropathic Pain.

Authors: Sonia Kartha; Lesan Yan; Meagan E Ita; Ahmad Amirshaghaghi; Lijun Luo; Yulong Wei; Andrew Tsourkas; Beth A Winkelstein; Zhiliang Cheng
Journal: ACS Nano Date: 2020-06-04 Impact factor: 15.881

4 in total