Literature DB >> 26138181

Does aortic valve sclerosis predicts the severity and complexity of coronary artery disease?

Hemal Bhatt1, Dharmesh Sanghani2, Kell Julliard2, George Fernaine3.   

Abstract

AIM: We assessed the association of aortic valve sclerosis (AVS) with atherosclerotic risk factors and severity and complexity of coronary artery disease (CAD).
METHODS: In this retrospective study, a total of 482 eligible patients were divided into 2 groups: AVS present and AVS absent. All major cardiovascular risk factors and coronary lesion characteristics were included.
RESULTS: Age was the only independent predictor of AVS. AVS was not independently associated with the number of obstructive vessels, degree of lesion obstruction and SYNTAX score.
CONCLUSION: AVS is probably a benign marker of age-related degenerative changes in the heart independent of the severity and complexity of CAD.
Copyright © 2015 Cardiological Society of India. Published by Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Aortic valve sclerosis; Coronary artery disease; SYNTAX score

Mesh:

Year:  2015        PMID: 26138181      PMCID: PMC4495668          DOI: 10.1016/j.ihj.2015.03.010

Source DB:  PubMed          Journal:  Indian Heart J        ISSN: 0019-4832


  14 in total

Review 1.  Spectrum of calcific aortic valve disease: pathogenesis, disease progression, and treatment strategies.

Authors:  Rosario V Freeman; Catherine M Otto
Journal:  Circulation       Date:  2005-06-21       Impact factor: 29.690

2.  Aortic valve sclerosis relates to cardiovascular events in patients with hypertension (a LIFE substudy).

Authors:  Michael H Olsen; Kristian Wachtell; Jonathan N Bella; Eva Gerdts; Vittorio Palmieri; Markku S Nieminen; Gunnar Smith; Hans Ibsen; Richard B Devereux
Journal:  Am J Cardiol       Date:  2005-01-01       Impact factor: 2.778

3.  Clinical factors associated with calcific aortic valve disease. Cardiovascular Health Study.

Authors:  B F Stewart; D Siscovick; B K Lind; J M Gardin; J S Gottdiener; V E Smith; D W Kitzman; C M Otto
Journal:  J Am Coll Cardiol       Date:  1997-03-01       Impact factor: 24.094

4.  Relationship between aortic valve sclerosis and the extent of coronary artery disease in patients undergoing diagnostic coronary angiography.

Authors:  Serdar Soydinc; Vedat Davutoglu; Ayhan Dundar; Mehmet Aksoy
Journal:  Cardiology       Date:  2006-05-29       Impact factor: 1.869

5.  The SYNTAX score and its clinical implications.

Authors:  Stuart J Head; Vasim Farooq; Patrick W Serruys; A Pieter Kappetein
Journal:  Heart       Date:  2013-03-28       Impact factor: 5.994

6.  Factors associated with calcific aortic valve degeneration in the elderly.

Authors:  M Lindroos; M Kupari; J Valvanne; T Strandberg; J Heikkilä; R Tilvis
Journal:  Eur Heart J       Date:  1994-07       Impact factor: 29.983

7.  Mitral and aortic annular calcification are highly associated with systemic calcified atherosclerosis.

Authors:  Matthew A Allison; Philip Cheung; Michael H Criqui; Robert D Langer; C Michael Wright
Journal:  Circulation       Date:  2006-02-06       Impact factor: 29.690

8.  Characterization of the early lesion of 'degenerative' valvular aortic stenosis. Histological and immunohistochemical studies.

Authors:  C M Otto; J Kuusisto; D D Reichenbach; A M Gown; K D O'Brien
Journal:  Circulation       Date:  1994-08       Impact factor: 29.690

9.  Interleukin-1 beta promotes matrix metalloproteinase expression and cell proliferation in calcific aortic valve stenosis.

Authors:  Jens J Kaden; Carl-Erik Dempfle; Rainer Grobholz; Hanh-Thai Tran; Refika Kiliç; Aslihan Sarikoç; Martina Brueckmann; Christian Vahl; Siegfried Hagl; Karl K Haase; Martin Borggrefe
Journal:  Atherosclerosis       Date:  2003-10       Impact factor: 5.162

10.  Aortic and mitral annular calcifications are predictive of all-cause and cardiovascular mortality in patients with type 2 diabetes.

Authors:  Andrea Rossi; Giovanni Targher; Giacomo Zoppini; Mariantonietta Cicoira; Stefano Bonapace; Carlo Negri; Vincenzo Stoico; Pompilio Faggiano; Corrado Vassanelli; Enzo Bonora
Journal:  Diabetes Care       Date:  2012-06-14       Impact factor: 19.112

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