| Literature DB >> 26137926 |
Xun Zhang1, Jing Li1, Hua Tian1, Yian Shi2,3,4.
Abstract
The dimeric cinchona alkaloid (DHQD)2 PHAL is used to catalyze an effective asymmetric bromohydroxylation of unfunctionalized olefins with H2 O as nucleophile an N-bromobenzamide as a bromine source. A variety of optically active bromohydrins are formed with up to 88 % ee.Entities:
Keywords: bromination; cinchona alkaloids; enantioselectivity; olefins; water
Year: 2015 PMID： 26137926 DOI： 10.1002/chem.201502133
Source DB: PubMed Journal: Chemistry ISSN： 0947-6539 Impact factor: 5.236