Literature DB >> 26137859

Design of a hyperpolarized (15)N NMR probe that induces a large chemical-shift change upon binding of calcium ions.

Ryunosuke Hata1, Hiroshi Nonaka, Yoichi Takakusagi, Kazuhiro Ichikawa, Shinsuke Sando.   

Abstract

Ca(2+) is a fundamental metal ion for physiological functioning. Therefore, molecular probes for Ca(2+) analysis are required. Recently, a hyperpolarized NMR probe has emerged as a promising tool. Here, we report a new design of a hyperpolarized NMR probe for Ca(2+), which showed a large chemical shift change upon binding to Ca(2+) and was applied for Ca(2+) sensing in a hyperpolarized state.

Entities:  

Mesh：

Substances：

Year:  2015        PMID： 26137859     DOI： 10.1039/c5cc04597e

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  9 in total

1.  Spin-Lattice Relaxation of Hyperpolarized Metronidazole in Signal Amplification by Reversible Exchange in Micro-Tesla Fields.

Authors:  Roman V Shchepin; Lamya Jaigirdar; Eduard Y Chekmenev
Journal:  J Phys Chem C Nanomater Interfaces       Date:  2018-02-27       Impact factor: 4.126

2.  A versatile synthetic route to the preparation of 15 N heterocycles.

Authors:  Nikita V Chukanov; Bryce E Kidd; Larisa M Kovtunova; Valerii I Bukhtiyarov; Roman V Shchepin; Eduard Y Chekmenev; Boyd M Goodson; Kirill V Kovtunov; Igor V Koptyug
Journal:  J Labelled Comp Radiopharm       Date:  2019-01-07       Impact factor: 1.921

3.  Background-Free Proton NMR Spectroscopy with Radiofrequency Amplification by Stimulated Emission Radiation.

Authors:  Baptiste Joalland; Thomas Theis; Stephan Appelt; Eduard Y Chekmenev
Journal:  Angew Chem Int Ed Engl       Date:  2021-10-01       Impact factor: 15.336

Review 4.  State-of-the-art accounts of hyperpolarized 15N-labeled molecular imaging probes for magnetic resonance spectroscopy and imaging.

Authors:  Hyejin Park; Qiu Wang
Journal:  Chem Sci       Date:  2022-05-17       Impact factor: 9.969

Review 5.  Synthetic Approaches for 15 N-Labeled Hyperpolarized Heterocyclic Molecular Imaging Agents for 15 N NMR Signal Amplification by Reversible Exchange in Microtesla Magnetic Fields.

Authors:  Nikita V Chukanov; Roman V Shchepin; Sameer M Joshi; Mohammad S H Kabir; Oleg G Salnikov; Alexandra Svyatova; Igor V Koptyug; Juri G Gelovani; Eduard Y Chekmenev
Journal:  Chemistry       Date:  2021-05-21       Impact factor: 5.020

6.  Over 20% (15)N Hyperpolarization in Under One Minute for Metronidazole, an Antibiotic and Hypoxia Probe.

Authors:  Danila A Barskiy; Roman V Shchepin; Aaron M Coffey; Thomas Theis; Warren S Warren; Boyd M Goodson; Eduard Y Chekmenev
Journal:  J Am Chem Soc       Date:  2016-06-23       Impact factor: 15.419

7.  Design of a 15N Molecular Unit to Achieve Long Retention of Hyperpolarized Spin State.

Authors:  Hiroshi Nonaka; Masashi Hirano; Yuki Imakura; Yoichi Takakusagi; Kazuhiro Ichikawa; Shinsuke Sando
Journal:  Sci Rep       Date:  2017-01-09       Impact factor: 4.379

8.  Generalizing, Extending, and Maximizing Nitrogen-15 Hyperpolarization Induced by Parahydrogen in Reversible Exchange.

Authors:  Johannes F P Colell; Angus W J Logan; Zijian Zhou; Roman V Shchepin; Danila A Barskiy; Gerardo X Ortiz; Qiu Wang; Steven J Malcolmson; Eduard Y Chekmenev; Warren S Warren; Thomas Theis
Journal:  J Phys Chem C Nanomater Interfaces       Date:  2017-02-02       Impact factor: 4.126

9.  Efficient Synthesis of Nicotinamide-1-¹⁵N for Ultrafast NMR Hyperpolarization Using Parahydrogen.

Authors:  Roman V Shchepin; Danila A Barskiy; Dmitry M Mikhaylov; Eduard Y Chekmenev
Journal:  Bioconjug Chem       Date:  2016-03-24       Impact factor: 4.774
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.