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Literature DB >> 26137408

STAT3 in arsenic lung carcinogenicity.

Abstract

We recently found that the chronic sterile inflammation contributes to arsenic lung tumorigenesis which is inhibited by autophagy. STAT3 regulates the interaction between inflammation and autophagy. STAT3 may also play a critical role in mediating the crosstalk between lung epithelial cells and their microenvironment, including immune cells, during arsenic lung carcinogenesis.

Entities: Disease Gene

Keywords: STAT3; arsenic; autophagy; immunosurveillance; lung tumorigenesis; microenvironment

Year: 2015 PMID： 26137408 PMCID： PMC4485752 DOI： 10.1080/2162402X.2014.995566

Source DB: PubMed Journal: Oncoimmunology ISSN： 2162-4011 Impact factor: 8.110

10 in total

Review 1. Autophagy and the immune system.

Authors: Petric Kuballa; Whitney M Nolte; Adam B Castoreno; Ramnik J Xavier
Journal: Annu Rev Immunol Date: 2012 Impact factor: 28.527

2. Mice lacking flt3 ligand have deficient hematopoiesis affecting hematopoietic progenitor cells, dendritic cells, and natural killer cells.

Authors: H J McKenna; K L Stocking; R E Miller; K Brasel; T De Smedt; E Maraskovsky; C R Maliszewski; D H Lynch; J Smith; B Pulendran; E R Roux; M Teepe; S D Lyman; J J Peschon
Journal: Blood Date: 2000-06-01 Impact factor: 22.113

3. Arsenic trioxide exerts antitumor activity through regulatory T cell depletion mediated by oxidative stress in a murine model of colon cancer.

Authors: Audrey Thomas-Schoemann; Frédéric Batteux; Céline Mongaret; Carole Nicco; Christiane Chéreau; Maxime Annereau; Alain Dauphin; François Goldwasser; Bernard Weill; François Lemare; Jérôme Alexandre
Journal: J Immunol Date: 2012-10-26 Impact factor: 5.422

Review 4. Autophagy in infection, inflammation and immunity.

Authors: Vojo Deretic; Tatsuya Saitoh; Shizuo Akira
Journal: Nat Rev Immunol Date: 2013-10 Impact factor: 53.106

5. Autophagy is a cell self-protective mechanism against arsenic-induced cell transformation.

Authors: Tao Zhang; Yuanlin Qi; Mingjun Liao; Mei Xu; Kimberley A Bower; Jacqueline A Frank; Han-Ming Shen; Jia Luo; Xianglin Shi; Gang Chen
Journal: Toxicol Sci Date: 2012-08-05 Impact factor: 4.849

6. Analysis of T-cell proliferation and cytokine secretion in the individuals exposed to arsenic.

Authors: R Biswas; P Ghosh; N Banerjee; J K Das; T Sau; A Banerjee; S Roy; S Ganguly; M Chatterjee; A Mukherjee; A K Giri
Journal: Hum Exp Toxicol Date: 2008-05 Impact factor: 2.903

7. Autophagy inhibition by sustained overproduction of IL6 contributes to arsenic carcinogenesis.

Authors: Yuanlin Qi; Mingfang Zhang; Hui Li; Jacqueline A Frank; Lu Dai; Huijuan Liu; Zhuo Zhang; Chi Wang; Gang Chen
Journal: Cancer Res Date: 2014-05-15 Impact factor: 12.701

8. Differential susceptibility of human peripheral blood T cells to suppression by environmental levels of sodium arsenite and monomethylarsonous acid.

Authors: Scott W Burchiel; Fredine T Lauer; Ellen J Beswick; A Jay Gandolfi; Faruque Parvez; Ke Jian Liu; Laurie G Hudson
Journal: PLoS One Date: 2014-10-01 Impact factor: 3.240

9. Chronic exposure to arsenic in the drinking water alters the expression of immune response genes in mouse lung.

Authors: Courtney D Kozul; Thomas H Hampton; Jennifer C Davey; Julie A Gosse; Athena P Nomikos; Phillip L Eisenhauer; Daniel J Weiss; Jessica E Thorpe; Michael A Ihnat; Joshua W Hamilton
Journal: Environ Health Perspect Date: 2009-03-04 Impact factor: 9.031

10. Involvement of STAT3 in immune evasion during lung tumorigenesis.

Authors: Hiroshi Kida; Shoichi Ihara; Atsushi Kumanogoh
Journal: Oncoimmunology Date: 2013-01-01 Impact factor: 8.110