Literature DB >> 26137375

Hybrid algorithm for simulating the collimated transmittance of homogeneous stratified turbid media.

Beatriz Morales Cruzado1, José Alberto Delgado Atencio2, Sergio Vázquez Y Montiel2, Erick Sarmiento Gómez3.   

Abstract

In this work we describe the development of a program that simulates the propagation of photons through refractive and reflecting optical components such as lenses, mirrors and stops that includes a biological tissue sample as the main issue to be investigated in order to get a simulated value of light distribution, in particular, of the unscattered light. The analysis of the photons that travel through the sample is based on the program Monte Carlo Multi-Layered with some modifications that consider a Gaussian beam as initial source of light. Position, directional cosines and weight of photons exiting the turbid media are used to propagate them through an optical system. As a mean of validation of the program, we selected a typical optical system for measurement of collimated transmittance. Therefore, several tests were carried out to find the optical system that gives the theoretical collimated transmittance at different values of the optical properties of the turbid media. Along this validation, the optimal experimental configuration is found. Using this results, a comparison between the simulated optimal configuration and the experimental set-up was done, by using a colloidal suspension as a turbid media.

Keywords:  (170.0170) Medical optics and biotechnology; (170.3660) Light propagation in tissues; (170.6935) Tissue characterization; (220.3620) Lens system design

Year:  2015        PMID: 26137375      PMCID: PMC4467723          DOI: 10.1364/BOE.6.001726

Source DB:  PubMed          Journal:  Biomed Opt Express        ISSN: 2156-7085            Impact factor:   3.732


  12 in total

1.  Experimental validation of Monte Carlo modeling of fluorescence in tissues in the UV-visible spectrum.

Authors:  Quan Liu; Changfang Zhu; Nirmala Ramanujam
Journal:  J Biomed Opt       Date:  2003-04       Impact factor: 3.170

2.  Determining the optical properties of turbid mediaby using the adding-doubling method.

Authors:  S A Prahl; M J van Gemert; A J Welch
Journal:  Appl Opt       Date:  1993-02-01       Impact factor: 1.980

3.  Measurements of the optical properties of tissue in conjunction with photodynamic therapy.

Authors:  A M Nilsson; R Berg; S Andersson-Engels
Journal:  Appl Opt       Date:  1995-07-20       Impact factor: 1.980

4.  Error estimation of measuring total interaction coefficients of turbid media using collimated light transmission.

Authors:  L Wang; S L Jacques
Journal:  Phys Med Biol       Date:  1994-12       Impact factor: 3.609

5.  Determination of optical properties of human blood in the spectral range 250 to 1100 nm using Monte Carlo simulations with hematocrit-dependent effective scattering phase functions.

Authors:  Moritz Friebel; André Roggan; Gerhard Müller; Martina Meinke
Journal:  J Biomed Opt       Date:  2006 May-Jun       Impact factor: 3.170

6.  Changes in optical properties of human whole blood in vitro due to slow heating.

Authors:  A M Nilsson; G W Lucassen; W Verkruysse; S Andersson-Engels; M J van Gemert
Journal:  Photochem Photobiol       Date:  1997-02       Impact factor: 3.421

7.  MCML--Monte Carlo modeling of light transport in multi-layered tissues.

Authors:  L Wang; S L Jacques; L Zheng
Journal:  Comput Methods Programs Biomed       Date:  1995-07       Impact factor: 5.428

8.  Optical properties of ocular fundus tissues--an in vitro study using the double-integrating-sphere technique and inverse Monte Carlo simulation.

Authors:  M Hammer; A Roggan; D Schweitzer; G Müller
Journal:  Phys Med Biol       Date:  1995-06       Impact factor: 3.609

9.  Numerical investigation of lens based setup for depth sensitive diffuse reflectance measurements in an epithelial cancer model.

Authors:  Caigang Zhu; Quan Liu
Journal:  Opt Express       Date:  2012-12-31       Impact factor: 3.894

10.  Genetic algorithms and MCML program for recovery of optical properties of homogeneous turbid media.

Authors:  Beatriz Morales Cruzado; Sergio Vázquez Y Montiel; José Alberto Delgado Atencio
Journal:  Biomed Opt Express       Date:  2013-02-15       Impact factor: 3.732

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