Literature DB >> 26137151

Omental transplantation improves surgical outcome of large squamous cell carcinoma: A case report.

Xianan Li1, Zhengxiao Ouyang2, Shuo Yang1, Zanjing Zhai3, Haowei Li3, Zhong-Cheng Kang4, Zan Li5.   

Abstract

Cutaneous squamous cell carcinoma (SCC) is an major health issue due to the significant health costs and marked disfigurement following surgical excision. The conventional reconstructive options may not be suitable for patients with large SCCs of the lower part of the leg, due to the regional tissue damage and ischemic environment. The omental transposition flap is a highly vascularized tissue that is resistant to infection and provides a recipient bed for skin grafts. This is the case report of a male patient with a large SCC in the lower part of his right leg, which was treated with extensive resection. The patient subsequently underwent reconstruction using a free omental flap, followed by transplantation of a secondary skin graft. The patient did not experience recurrence or metastasis during the 2 years of follow-up, indicating that, when dealing with postoperative skin cancer defects in an ischemic environment, omental transplantation may be a viable treatment option.

Entities:  

Keywords:  limb-salvage surgery; non-melanoma skin cancer; omental transplantation; skin defect reconstruction; squamous cell carcinoma

Year:  2015        PMID: 26137151      PMCID: PMC4473671          DOI: 10.3892/ol.2015.3089

Source DB:  PubMed          Journal:  Oncol Lett        ISSN: 1792-1074            Impact factor:   2.967


  12 in total

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Journal:  N Engl J Med       Date:  2001-03-29       Impact factor: 91.245

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Authors:  Daniel Belkin; John A Carucci
Journal:  Dermatol Clin       Date:  2011-04       Impact factor: 3.478

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Authors:  John F McGuire; Norman N Ge; Senait Dyson
Journal:  Am J Otolaryngol       Date:  2008-07-22       Impact factor: 1.808

8.  Guidelines for the management of squamous cell carcinoma in organ transplant recipients.

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10.  Tumor recurrence 5 years after treatment of cutaneous basal cell carcinoma and squamous cell carcinoma.

Authors:  Mary-Margaret Chren; Eleni Linos; Jeanette S Torres; Sarah E Stuart; Rupa Parvataneni; W John Boscardin
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  2 in total

1.  [Application of pedicled omentum flap in breast reconstruction of breast cancer patients].

Authors:  Nengbin Wan; Dequan Liu; Lingli Lu; Xiao He; Dajiang Song; Zan Li; Xiao Zhou; Wen Peng; Zeyang Liu
Journal:  Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi       Date:  2019-08-15

2.  Iontophoresis Improved Growth Reduction of Invasive Squamous Cell Carcinoma in Topical Photodynamic Therapy.

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Journal:  PLoS One       Date:  2016-01-11       Impact factor: 3.240

  2 in total

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