Literature DB >> 26136953

Sporadic lymphangioleiomyomatosis with bloody sputum as an initial symptom: A case report and review of the literature.

Kai Wu1, Hui-Yu Lu1.   

Abstract

Lymphangioleiomyomatosis (LAM) is an extremely rare lung disease affecting females of a childbearing age. The condition occurs sporadically or in association with tuberous sclerosis complex. The diagnosis of LAM is often delayed since the clinical symptoms and signs are non-specific. The present study reports the a case of a patient with LAM, in which bloody sputum was presented as the initial symptom. The 43-year-old female had experienced a small amount of bloody sputum over the previous five years. The patient was admitted to the Department of Respiratory Medicine at Taizhou People's Hospital (Taizhou, China) in 2012, reporting symptoms of a cough, shortness of breath and bloody sputum over the previous 10 days. A high-resolution computed tomography scan revealed multiple small circular thin-walled translucent areas in both lung fields. The initial diagnosis of the patient was LAM. A biopsy was performed using a video-assisted thoracoscopy. In conclusion, increased awareness and early diagnosis and treatment were determined to be key factors in ensuring a satisfactory prognosis.

Entities:  

Keywords:  chylous pleural effusions; diagnosis; lymphangioleiomyomatosis; therapy

Year:  2015        PMID: 26136953      PMCID: PMC4473337          DOI: 10.3892/etm.2015.2397

Source DB:  PubMed          Journal:  Exp Ther Med        ISSN: 1792-0981            Impact factor:   2.447


  36 in total

1.  [Lymphangioleiomyomatosis: new therapeutic approaches].

Authors:  Alvaro Casanova; Julio Ancochea
Journal:  Arch Bronconeumol       Date:  2011-09-15       Impact factor: 4.872

2.  Pregnancy exacerbating unsuspected mediastinal lymphangioleiomyomatosis and chylothorax.

Authors:  A Brunelli; G Catalini; A Fianchini
Journal:  Int J Gynaecol Obstet       Date:  1996-03       Impact factor: 3.561

3.  Decline in lung function in patients with lymphangioleiomyomatosis treated with or without progesterone.

Authors:  Angelo M Taveira-DaSilva; Mario P Stylianou; Carolyn J Hedin; Olanda Hathaway; Joel Moss
Journal:  Chest       Date:  2004-12       Impact factor: 9.410

4.  Prognostic significance of pulmonary lymphangioleiomyomatosis histologic score.

Authors:  K Matsui; M B Beasley; W K Nelson; P M Barnes; J Bechtle; R Falk; V J Ferrans; J Moss; W D Travis
Journal:  Am J Surg Pathol       Date:  2001-04       Impact factor: 6.394

5.  Clinical trials for rare lung diseases: lessons from lymphangioleiomyomatosis.

Authors:  Brent Kinder; Francis X McCormack
Journal:  Lymphat Res Biol       Date:  2010-03       Impact factor: 2.589

6.  Exacerbation of pulmonary lymphangioleiomyomatosis by exogenous oestrogen used for infertility treatment.

Authors:  S Yano
Journal:  Thorax       Date:  2002-12       Impact factor: 9.139

7.  Chronic cystic lung disease: diagnostic accuracy of high-resolution CT in 92 patients.

Authors:  Mitsuhiro Koyama; Takeshi Johkoh; Osamu Honda; Mitsuko Tsubamoto; Takenori Kozuka; Noriyuki Tomiyama; Seiki Hamada; Hironobu Nakamura; Masanori Akira; Kazuya Ichikado; Kiminori Fujimoto; Toru Rikimaru; Ukihide Tateishi; Nestor L Müller
Journal:  AJR Am J Roentgenol       Date:  2003-03       Impact factor: 3.959

8.  Activation of the estrogen receptor contributes to the progression of pulmonary lymphangioleiomyomatosis via matrix metalloproteinase-induced cell invasiveness.

Authors:  Marilyn K Glassberg; Sharon J Elliot; Jason Fritz; Paola Catanuto; Mylene Potier; Roger Donahue; William Stetler-Stevenson; Michael Karl
Journal:  J Clin Endocrinol Metab       Date:  2008-02-19       Impact factor: 5.958

Review 9.  Smooth muscle-like cells in pulmonary lymphangioleiomyomatosis.

Authors:  Vera P Krymskaya
Journal:  Proc Am Thorac Soc       Date:  2008-01-01

10.  Estradiol and tamoxifen stimulate LAM-associated angiomyolipoma cell growth and activate both genomic and nongenomic signaling pathways.

Authors:  Jane Yu; Aristotelis Astrinidis; Sharon Howard; Elizabeth Petri Henske
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2003-08-15       Impact factor: 5.464

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