PURPOSE: The purpose of this study was to research the use of near-infrared spectroscopy (NIRS) on the neurocognitive functions in the patients undergoing coronary artery bypass grafting (CABG) with asymptomatic carotid artery disease. METHODS: The study design was carried out with the participation of 79 patients in a prospective, randomized and double blind control method. The patients were separated into two groups as NIRS (n = 43) and no NIRS (n = 36). A neurocognitive test was applied preoperatively and postoperatively to all patients before discharge. Cognitive functions were evaluated by applying the Montreal Cognitive Assessment test (MoCA). RESULTS: The decrease in the postoperative score of mean MoCA in no NIRS group was statistically significant when compared to preoperatively (p <0.001). Postoperative mean MoCA score was found to be significantly higher in NIRS group (NIRS: 26.8 ± 1.9 vs. no NIRS: 23.6 ± 2.5, p <0.001). It has been determined that there was a moderately positive significant correlation between the increase in the NIRS used patients (%) and increase in the MoCA score of the patients (r = 0.59, p <0.001). CONCLUSION: Intraoperative NIRS usage in the patients undergoing CABG with carotid artery disease might be useful due to its postoperative positive effects on the cognitive functions.
RCT Entities:
PURPOSE: The purpose of this study was to research the use of near-infrared spectroscopy (NIRS) on the neurocognitive functions in the patients undergoing coronary artery bypass grafting (CABG) with asymptomatic carotid artery disease. METHODS: The study design was carried out with the participation of 79 patients in a prospective, randomized and double blind control method. The patients were separated into two groups as NIRS (n = 43) and no NIRS (n = 36). A neurocognitive test was applied preoperatively and postoperatively to all patients before discharge. Cognitive functions were evaluated by applying the Montreal Cognitive Assessment test (MoCA). RESULTS: The decrease in the postoperative score of mean MoCA in no NIRS group was statistically significant when compared to preoperatively (p <0.001). Postoperative mean MoCA score was found to be significantly higher in NIRS group (NIRS: 26.8 ± 1.9 vs. no NIRS: 23.6 ± 2.5, p <0.001). It has been determined that there was a moderately positive significant correlation between the increase in the NIRS used patients (%) and increase in the MoCA score of the patients (r = 0.59, p <0.001). CONCLUSION: Intraoperative NIRS usage in the patients undergoing CABG with carotid artery disease might be useful due to its postoperative positive effects on the cognitive functions.
Authors: M F Newman; J L Kirchner; B Phillips-Bute; V Gaver; H Grocott; R H Jones; D B Mark; J G Reves; J A Blumenthal Journal: N Engl J Med Date: 2001-02-08 Impact factor: 91.245
Authors: Mark F Newman; Joseph P Mathew; Hilary P Grocott; G Burkhard Mackensen; Terri Monk; Kathleen A Welsh-Bohmer; James A Blumenthal; Daniel T Laskowitz; Daniel B Mark Journal: Lancet Date: 2006-08-19 Impact factor: 79.321
Authors: C W Akins; A C Moncure; W M Daggett; R P Cambria; A D Hilgenberg; D F Torchiana; G J Vlahakes Journal: Ann Thorac Surg Date: 1995-08 Impact factor: 4.330
Authors: E P Mahanna; J A Blumenthal; W D White; N D Croughwell; C P Clancy; L R Smith; M F Newman Journal: Ann Thorac Surg Date: 1996-05 Impact factor: 4.330
Authors: Mathias Lühr Hansen; Simon Hyttel-Sørensen; Janus Christian Jakobsen; Christian Gluud; Elisabeth M W Kooi; Jonathan Mintzer; Willem P de Boode; Monica Fumagalli; Ana Alarcon; Thomas Alderliesten; Gorm Greisen Journal: Pediatr Res Date: 2022-02-22 Impact factor: 3.756
Authors: Christian Ortega-Loubon; Francisco Herrera-Gómez; Coralina Bernuy-Guevara; Pablo Jorge-Monjas; Carlos Ochoa-Sangrador; Juan Bustamante-Munguira; Eduardo Tamayo; F Javier Álvarez Journal: J Clin Med Date: 2019-12-14 Impact factor: 4.241