Literature DB >> 26132826

Viral Load in Infants Hospitalized for Respiratory Syncytial Virus Bronchiolitis Correlates with Recurrent Wheezing at Thirty-Six-Month Follow-Up.

Raffaella Nenna1, Marianna Ferrara, Ambra Nicolai, Alessandra Pierangeli, Carolina Scagnolari, Paola Papoff, Guido Antonelli, Corrado Moretti, Fabio Midulla.   

Abstract

The relationship between viral infection, host immune response in infants with respiratory syncytial virus (RSV) bronchiolitis and subsequent wheezing is discussed. We measured RSV-RNA load and interferon-λ1-3 expression in the nasopharyngeal washings from 68 infants hospitalized for RSV bronchiolitis, and wheezing was assessed 36 months after the first episode of bronchiolitis. Higher RSV-RNA load and higher interferon-λ2/3 levels were found in children with recurrent wheezing at 36-month follow-up.

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Year:  2015        PMID： 26132826     DOI： 10.1097/INF.0000000000000825

Source DB:  PubMed          Journal:  Pediatr Infect Dis J        ISSN： 0891-3668            Impact factor:   2.129


  12 in total

1.  Innate IFN-lambda responses to dsRNA in the human infant airway epithelium and clinical regulatory factors during viral respiratory infections in early life.

Authors:  Kyle Salka; Maria Arroyo; Elizabeth Chorvinsky; Karima Abutaleb; Geovanny F Perez; Seth Wolf; Xilei Xuchen; Jered Weinstock; Maria J Gutierrez; Marcos Pérez-Losada; Dinesh K Pillai; Gustavo Nino
Journal:  Clin Exp Allergy       Date:  2020-07-26       Impact factor: 5.018

Review 2.  Best practice in the prevention and management of paediatric respiratory syncytial virus infection.

Authors:  Simon B Drysdale; Christopher A Green; Charles J Sande
Journal:  Ther Adv Infect Dis       Date:  2016-02-10

Review 3.  The Human Immune Response to Respiratory Syncytial Virus Infection.

Authors:  Clark D Russell; Stefan A Unger; Marc Walton; Jürgen Schwarze
Journal:  Clin Microbiol Rev       Date:  2017-04       Impact factor: 26.132

Review 4.  The Burden and Long-term Respiratory Morbidity Associated with Respiratory Syncytial Virus Infection in Early Childhood.

Authors:  Brigitte Fauroux; Eric A F Simões; Paul A Checchia; Bosco Paes; Josep Figueras-Aloy; Paolo Manzoni; Louis Bont; Xavier Carbonell-Estrany
Journal:  Infect Dis Ther       Date:  2017-03-29

Review 5.  Viral bronchiolitis.

Authors:  Todd A Florin; Amy C Plint; Joseph J Zorc
Journal:  Lancet       Date:  2016-08-20       Impact factor: 79.321

6.  Acute bronchiolitis: Influence of viral co-infection in infants hospitalized over 12 consecutive epidemic seasons.

Authors:  Laura Petrarca; Raffaella Nenna; Antonella Frassanito; Alessandra Pierangeli; Salvatore Leonardi; Carolina Scagnolari; Guido Antonelli; Paola Papoff; Corrado Moretti; Fabio Midulla
Journal:  J Med Virol       Date:  2017-12-11       Impact factor: 2.327

7.  Impact of the 2014 American Academy of Pediatrics recommendation and of the resulting limited financial coverage by the Italian Medicines Agency for palivizumab prophylaxis on the RSV-associated hospitalizations in preterm infants during the 2016-2017 epidemic season: a systematic review of seven Italian reports.

Authors:  Renato Cutrera; Andrea Wolfler; Simonetta Picone; Giovanni A Rossi; Giuliana Gualberti; Rocco Merolla; Antonio Del Vecchio; Alberto Villani; Fabio Midulla; Andrea Dotta
Journal:  Ital J Pediatr       Date:  2019-11-09       Impact factor: 2.638

Review 8.  MicroRNAs: Mediators and Therapeutic Targets to Airway Hyper Reactivity After Respiratory Syncytial Virus Infection.

Authors:  Shuwen Feng; Dongxin Zeng; Junwen Zheng; Dongchi Zhao
Journal:  Front Microbiol       Date:  2018-09-11       Impact factor: 5.640

Review 9.  Issues in vaccinology: Present challenges and future directions.

Authors:  Dylan Sheerin; Peter Jm Openshaw; Andrew J Pollard
Journal:  Eur J Immunol       Date:  2017-09-27       Impact factor: 5.532

10.  RSV-hRV co-infection is a risk factor for recurrent bronchial obstruction and early sensitization 3 years after bronchiolitis.

Authors:  Flore Amat; Chloé Plantard; Aurélien Mulliez; Isabelle Petit; Emmanuelle Rochette; Matthieu Verdan; Cécile Henquell; Guillaume Labbé; Marie Christine Heraud; Bertrand Evrard; André Labbé
Journal:  J Med Virol       Date:  2018-02-15       Impact factor: 2.327
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