Literature DB >> 2613254

Genetic relationships of Europeans, Asians and Africans and the origin of modern Homo sapiens.

M Nei1, G Livshits.   

Abstract

To study the evolutionary relationships of the three major groups of humans, Europeans, Asians and Africans, the genetic distances between them were computed by using 4 different sets of genetic loci (84 protein loci, 33 blood group loci, 8 HLA and immunoglobulin loci, and 61 DNA markers). The results obtained indicate that the overall genetic distance between Europeans and Asians is significantly lower than that between Europeans and Africans of that between Asians and Africans and support the hypothesis of an African origin of modern humans. This seems to be the first study to establish the evolutionary relationships of the three major groups of humans at a statistically significant level.

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Year:  1989        PMID： 2613254     DOI： 10.1159/000153872

Source DB:  PubMed          Journal:  Hum Hered        ISSN： 0001-5652            Impact factor:   0.444


  15 in total

1.  Genetic evidence on the origins of Indian caste populations.

Authors:  M Bamshad; T Kivisild; W S Watkins; M E Dixon; C E Ricker; B B Rao; J M Naidu; B V Prasad; P G Reddy; A Rasanayagam; S S Papiha; R Villems; A J Redd; M F Hammer; S V Nguyen; M L Carroll; M A Batzer; L B Jorde
Journal:  Genome Res       Date:  2001-06       Impact factor: 9.043

2.  Extensive genetic diversity in the HLA class II region of Africans, with a focally predominant allele, DRB1*1304.

Authors:  A V Hill; C E Allsopp; D Kwiatkowski; T E Taylor; S N Yates; N M Anstey; J J Wirima; D R Brewster; A J McMichael; M E Molyneux
Journal:  Proc Natl Acad Sci U S A       Date:  1992-03-15       Impact factor: 11.205

3.  Geographical, environmental and pathophysiological influences on the human blood transcriptome.

Authors:  Rubina Tabassum; Artika Nath; Marcela Preininger; Greg Gibson
Journal:  Curr Genet Med Rep       Date:  2013-12

4.  Effects of natural selection on interpopulation divergence at polymorphic sites in human protein-coding Loci.

Authors:  Austin L Hughes; Bernice Packer; Robert Welch; Andrew W Bergen; Stephen J Chanock; Meredith Yeager
Journal:  Genetics       Date:  2005-05-23       Impact factor: 4.562

5.  Interethnic genetic differentiation in Africa: HLA class I antigens in The Gambia.

Authors:  C E Allsopp; R M Harding; C Taylor; M Bunce; D Kwiatkowski; N Anstey; D Brewster; A J McMichael; B M Greenwood; A V Hill
Journal:  Am J Hum Genet       Date:  1992-02       Impact factor: 11.025

6.  Drift, admixture, and selection in human evolution: a study with DNA polymorphisms.

Authors:  A M Bowcock; J R Kidd; J L Mountain; J M Hebert; L Carotenuto; K K Kidd; L L Cavalli-Sforza
Journal:  Proc Natl Acad Sci U S A       Date:  1991-02-01       Impact factor: 11.205

7.  mtDNA polymorphism in East Asian Populations, with special reference to the peopling of Japan.

Authors:  S Horai; K Murayama; K Hayasaka; S Matsubayashi; Y Hattori; G Fucharoen; S Harihara; K S Park; K Omoto; I H Pan
Journal:  Am J Hum Genet       Date:  1996-09       Impact factor: 11.025

8.  HLA polymorphism in the Havasupai: evidence for balancing selection.

Authors:  T Markow; P W Hedrick; K Zuerlein; J Danilovs; J Martin; T Vyvial; C Armstrong
Journal:  Am J Hum Genet       Date:  1993-10       Impact factor: 11.025

9.  Characterization of hypervariable locus-specific probes derived from a (CAC)5/(GTG)5 multilocus fingerprint in various Eurasian populations.

Authors:  J Hundrieser; P Nürnberg; A E Czeizel; J Métneki; S Rothgänger; H Zischler; J T Epplen
Journal:  Hum Genet       Date:  1992 Sep-Oct       Impact factor: 4.132

10.  Microsatellite diversity and the demographic history of modern humans.

Authors:  L B Jorde; A R Rogers; M Bamshad; W S Watkins; P Krakowiak; S Sung; J Kere; H C Harpending
Journal:  Proc Natl Acad Sci U S A       Date:  1997-04-01       Impact factor: 11.205
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