| Literature DB >> 26131954 |
Jiang-Kai Qiu1,2, Bo Jiang1, Yi-Long Zhu1,2, Wen-Juan Hao1, De-Cai Wang2, Jun Sun1,2, Ping Wei2, Shu-Jiang Tu1, Guigen Li3.
Abstract
A catalytic domino spirocyclization of 1,7-enynes with simple cycloalkanes and cyclo-1,3-dicarbonyls has been established via multiple C-C bond formations from alkynyl/alkenyl functions and dual α,α-C(sp(3))-H abstraction/insertion. The reaction involves addition, 6-exo-dig cyclization and radical coupling sequences under convenient catalytic conditions and provides a concise access to spiro cyclopenta[c]quinolines in good to excellent yields.Entities:
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Year: 2015 PMID： 26131954 DOI： 10.1021/jacs.5b05735
Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419