Literature DB >> 26131332

Gastrointestinal stromal tumour presenting as palpable abdominal mass: A rare entity.

Manoj R Bhambare1, Jayashri S Pandya1, Sudatta B Waghmare1, Tilakdas S Shetty1.   

Abstract

Gastrointestinal stromal tumours (GISTs) are the most common mesenchymal tumour of gastro-intestinal tract. Annual incidence of GIST in United States is approximately 3000-4000. Clinical presentation of GIST varies with location and size of tumour but GIST presenting with palpable abdominal mass is rare. We report a case of 38 years old male who presented with large abdominal lump. Computed tomography (CT) scan showed a large solid-cystic lesion encasing second part of duodenum and distal common bile duct. On CT differential diagnosis of Leiomyoma, Leiomyosarcoma and GIST were made. The diagnosis of GIST was confirmed by immune-histochemical study of the biopsy material. Patient underwent pancreaticodudenectomy. Post-operative course was uneventful. Patient was started on Imatinib therapy post-operatively. No recurrence noted at six months follow up.

Entities:  

Keywords:  Abdominal mass; Gastrointestinal stromal tumours; Imatinib; Pancreaticoduodenectomy

Year:  2015        PMID: 26131332      PMCID: PMC4478562          DOI: 10.4240/wjgs.v7.i6.98

Source DB:  PubMed          Journal:  World J Gastrointest Surg


  8 in total

1.  Two hundred gastrointestinal stromal tumors: recurrence patterns and prognostic factors for survival.

Authors:  R P DeMatteo; J J Lewis; D Leung; S S Mudan; J M Woodruff; M F Brennan
Journal:  Ann Surg       Date:  2000-01       Impact factor: 12.969

Review 2.  Gastrointestinal stromal tumors: a case report and review of the literature.

Authors:  Patrick Laperouse; Daniel Raines; Karen Diamond; Sammy Rivera; William Newman; Alfred Y Hew; Fred A Lopez
Journal:  J La State Med Soc       Date:  2008 May-Jun

3.  The CD117 immunohistochemistry tissue microarray survey for quality assurance and interlaboratory comparison: a College of American Pathologists Cell Markers Committee Study.

Authors:  David M Dorfman; Marilyn M Bui; Raymond R Tubbs; Eric D Hsi; Patrick L Fitzgibbons; Michael D Linden; Robert R Rickert; Patrick C Roche
Journal:  Arch Pathol Lab Med       Date:  2006-06       Impact factor: 5.534

4.  Gastrointestinal stromal tumors, intramural leiomyomas, and leiomyosarcomas in the duodenum: a clinicopathologic, immunohistochemical, and molecular genetic study of 167 cases.

Authors:  Markku Miettinen; Janusz Kopczynski; Hala R Makhlouf; Maarit Sarlomo-Rikala; Hajnalka Gyorffy; Allen Burke; Leslie H Sobin; Jerzy Lasota
Journal:  Am J Surg Pathol       Date:  2003-05       Impact factor: 6.394

Review 5.  Gastrointestinal stromal tumors (GISTs): a pathology view point.

Authors:  Pattana Sornmayura
Journal:  J Med Assoc Thai       Date:  2009-01

6.  Adjuvant imatinib mesylate after resection of localised, primary gastrointestinal stromal tumour: a randomised, double-blind, placebo-controlled trial.

Authors:  Ronald P Dematteo; Karla V Ballman; Cristina R Antonescu; Robert G Maki; Peter W T Pisters; George D Demetri; Martin E Blackstein; Charles D Blanke; Margaret von Mehren; Murray F Brennan; Shreyaskumar Patel; Martin D McCarter; Jonathan A Polikoff; Benjamin R Tan; Kouros Owzar
Journal:  Lancet       Date:  2009-03-18       Impact factor: 79.321

7.  Giant gastrointestinal stromal tumor presenting as a palpable abdominal mass: an unusual presentation.

Authors:  Sachin Patil; Sudhir Jain; R C M Kaza; Ronald S Chamberlain
Journal:  ISRN Surg       Date:  2011-06-16

8.  Gastrointestinal stromal tumors: a review of case reports, diagnosis, treatment, and future directions.

Authors:  Christopher B Tan; Wanqing Zhi; Ghulamullah Shahzad; Paul Mustacchia
Journal:  ISRN Gastroenterol       Date:  2012-04-12
  8 in total
  1 in total

1.  Surgical treatment of gastrointestinal stromal tumors of the duodenum: a literature review.

Authors:  Georgi Popivanov; Mihail Tabakov; George Mantese; Roberto Cirocchi; Irene Piccinini; Vito D'Andrea; Piero Covarelli; Carlo Boselli; Francesco Barberini; Renata Tabola; Ursi Pietro; Davide Cavaliere
Journal:  Transl Gastroenterol Hepatol       Date:  2018-09-21
  1 in total

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