Prostate calculi can higher urinary retention probability and worsen uncomfortable feeling after prostate biopsy but not predict cancer.

To investigate whether prostatic calculi might influence the urinary retention (UR) probability, the quality of life (QOL) and the positive rate of cancer after prostate biopsy in middle-aged and old male with PSA higher than normal. This study comprised a retrospective analysis of data from 685 patients (prostatic calculi group 325 VS non-prostatic calculi group 360), those who had undergone transrectal ultrasound-guided prostate needle biopsy (TRUS PNB) from Sept. 2012 to Sept. 2014. To these people, prostate volumes (PV) were recorded by TRUS and prostatic calculi were defined as present or absent. Other variables such as age, International Prostate Symptoms Score (IPSS), the quality of life (QOL), total PSA (prostate specific antigen) rate, and urinary retention cases were also recorded and compared. Among these patients, 154 (prostatic calculi group 73 VS non-prostatic calculi group 81) were diagnosed with prostate cancer through postoperative pathological, there was no significant difference between the two groups. But compared to the non-prostatic calculi group, after the prostate biopsy, the group with prostatic calculi experienced more uncomfortable feelings and enjoyed higher Urinary retention probability. Prostatic calculi could worsen QOL and higher urinary retention probability after transrectal ultrasound-guided prostate needle biopsy, but it is a weak predictor of positive results of prostate cancer in middle-aged and old male with PSA higher than normal.