Quan V Hoang1, Ching-Lung Chen2, Jose Garcia-Arumi3, Pamela R Sherwood1, Stanley Chang1. 1. Department of Ophthalmology, Edward S. Harkness Eye Institute, Columbia University College of Physicians and Surgeons, New York, New York, USA. 2. Department of Ophthalmology, Edward S. Harkness Eye Institute, Columbia University College of Physicians and Surgeons, New York, New York, USA Department of Ophthalmology, Chang Gung Memorial Hospital, Chiayi, Taiwan. 3. Department of Ophthalmology, Hospital Universitario Vall d'Hebrón, Barcelona, Spain.
Abstract
BACKGROUND: Myopic foveoschisis is the splitting of retinal layers overlying staphyloma in highly myopic patients that can lead to vision loss. We assess possible contributing mechanisms to the formation of foveoschisis by examining two cases of spontaneous improvement of myopic foveoschisis and employ a radius of curvature (ROC) measure to track posterior scleral curvature over time. METHODS: A retrospective, non-comparative case series was performed and optical coherence tomography images were analysed. Retinal pigment epithelial layer ROC was calculated from manually segmented images through the posterior scleral curvature apex. RESULTS: Two cases of myopic foveoschisis with foveal detachments in the left eye (OS) were studied. Both patients had high myopia (either <-10 D or >30 mm in axial length). One case occurred in a treatment-naive patient who improved after 4 months of observation. On initial presentation, OS posterior scleral ROC was 12.35 mm and decreased to 12.15 mm at the time of resolution. The other case occurred in a patient who was followed for 7 years, had previously underwent pars plana vitrectomy and removal of epiretinal membrane, experienced recurrence of foveoschisis and then spontaneously improved without further posterior segment surgery. There was an uncomplicated cataract extraction in the interim. Posterior scleral ROC was 4.05 mm on presentation, 4.10 during recurrence, 3.55 mm after cataract extraction and 3.75 mm at resolution. CONCLUSIONS: Spontaneous improvement of myopic foveoschisis may be due to changes in tractional forces from the internal limiting membrane, cortical vitreous or staphyloma or, alternatively, from a delayed or fluctuant recovery course after intervention. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/
BACKGROUND:Myopic foveoschisis is the splitting of retinal layers overlying staphyloma in highly myopic patients that can lead to vision loss. We assess possible contributing mechanisms to the formation of foveoschisis by examining two cases of spontaneous improvement of myopic foveoschisis and employ a radius of curvature (ROC) measure to track posterior scleral curvature over time. METHODS: A retrospective, non-comparative case series was performed and optical coherence tomography images were analysed. Retinal pigment epithelial layer ROC was calculated from manually segmented images through the posterior scleral curvature apex. RESULTS: Two cases of myopic foveoschisis with foveal detachments in the left eye (OS) were studied. Both patients had high myopia (either <-10 D or >30 mm in axial length). One case occurred in a treatment-naive patient who improved after 4 months of observation. On initial presentation, OS posterior scleral ROC was 12.35 mm and decreased to 12.15 mm at the time of resolution. The other case occurred in a patient who was followed for 7 years, had previously underwent pars plana vitrectomy and removal of epiretinal membrane, experienced recurrence of foveoschisis and then spontaneously improved without further posterior segment surgery. There was an uncomplicated cataract extraction in the interim. Posterior scleral ROC was 4.05 mm on presentation, 4.10 during recurrence, 3.55 mm after cataract extraction and 3.75 mm at resolution. CONCLUSIONS: Spontaneous improvement of myopic foveoschisis may be due to changes in tractional forces from the internal limiting membrane, cortical vitreous or staphyloma or, alternatively, from a delayed or fluctuant recovery course after intervention. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/
Authors: Bingyao Tan; Ryan P McNabb; Feihui Zheng; Yin Ci Sim; Xinwen Yao; Jacqueline Chua; Marcus Ang; Quan V Hoang; Anthony N Kuo; Leopold Schmetterer Journal: Biomed Opt Express Date: 2021-08-23 Impact factor: 3.732
Authors: Kai Yuan Tey; Qiu Ying Wong; Yee Shan Dan; Andrew S H Tsai; Daniel S W Ting; Marcus Ang; Gemmy Chiu Ming Cheung; Shu Yen Lee; Tien Yin Wong; Quan V Hoang; Chee Wai Wong Journal: Invest Ophthalmol Vis Sci Date: 2021-06-01 Impact factor: 4.799
Authors: Kai Yuan Tey; Quan V Hoang; Isabella Q Loh; Yee Shan Dan; Qiu Ying Wong; Daryle Jason G Yu; Vivi R Yandri; Marcus Ang; Gemmy C M Cheung; Shu Yen Lee; Tien Yin Wong; Rachel S Chong; Chee Wai Wong Journal: Front Med (Lausanne) Date: 2022-01-04