Luis G Tulloch1, Jeannie D Chan2, David J Carlbom3, Mary Jo Kelly4, Timothy H Dellit5, John B Lynch5. 1. 1 Department of Medicine, University of Washington and Veterans Affairs Puget Sound Health Care System, Seattle, WA, USA. 2. 2 Department of Pharmacy, Harborview Medical Center, and School of Pharmacy, University of Washington, Seattle, WA, USA. 3. 3 Division of Pulmonary and Critical Care Medicine, Department of Medicine, Harborview Medical Center and School of Medicine, University of Washington, Seattle, WA, USA. 4. 4 Department of Nursing, Harborview Medical Center, Seattle, WA, USA. 5. 5 Division of Allergy & Infectious Diseases, Department of Medicine, Harborview Medical Center and School of Medicine, University of Washington, Seattle, WA, USA.
Abstract
PURPOSE: To use the 2010 to 2011 data collected by structured chart review to provide a detailed up-to-date description of the epidemiology and microbiology of the sepsis syndromes. METHODS: Prospective observational study conducted at a university-affiliated urban teaching hospital and level-1 trauma and burn center. All adult patients who triggered a Code Sepsis in the emergency department (ED) between January 2010 and December 2011 were included. RESULTS: One hundred eighty four patients presented with a verified sepsis syndrome and triggered a Code Sepsis in the ED during the studied time period. The mean hospital and intensive care unit length of stays (LOSs) were 15.4 (interquartile range [IQR] = 14) and 6.7 (IQR = 5) days, respectively. The total inpatient mortality was 19% (n = 35). Patients with an unspecified source of infection and those without an isolated pathogen had the highest inpatient mortality, 42.1% (n = 8) and 23.3% (n = 10), respectively. CONCLUSION: Hospital mortality and hospital LOS of sepsis are similar to those reported in other observational studies. Our study confirms a decline in the mortality of sepsis predicted by earlier longitudinal studies and should prompt a resurgence of epidemiological research of the sepsis syndromes in the United States.
PURPOSE: To use the 2010 to 2011 data collected by structured chart review to provide a detailed up-to-date description of the epidemiology and microbiology of the sepsis syndromes. METHODS: Prospective observational study conducted at a university-affiliated urban teaching hospital and level-1 trauma and burn center. All adult patients who triggered a Code Sepsis in the emergency department (ED) between January 2010 and December 2011 were included. RESULTS: One hundred eighty four patients presented with a verified sepsis syndrome and triggered a Code Sepsis in the ED during the studied time period. The mean hospital and intensive care unit length of stays (LOSs) were 15.4 (interquartile range [IQR] = 14) and 6.7 (IQR = 5) days, respectively. The total inpatient mortality was 19% (n = 35). Patients with an unspecified source of infection and those without an isolated pathogen had the highest inpatient mortality, 42.1% (n = 8) and 23.3% (n = 10), respectively. CONCLUSION: Hospital mortality and hospital LOS of sepsis are similar to those reported in other observational studies. Our study confirms a decline in the mortality of sepsis predicted by earlier longitudinal studies and should prompt a resurgence of epidemiological research of the sepsis syndromes in the United States.
Authors: Kristina E Rudd; Niranjan Kissoon; Direk Limmathurotsakul; Sotharith Bory; Birungi Mutahunga; Christopher W Seymour; Derek C Angus; T Eoin West Journal: Crit Care Date: 2018-09-23 Impact factor: 9.097
Authors: Signe Trille Sørensen; S M Osama Bin Abdullah; Rune Husås Sørensen; Ram Dessau; Niels Høiby; Finn Erland Nielsen Journal: Int J Emerg Med Date: 2021-07-23