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Literature DB >> 26130225

Soluble RAGEs - Prospects for treating & tracking metabolic and inflammatory disease.

Abstract

Emerging evidence links the receptor for advanced glycation endproducts (RAGE) to the pathogenesis of tissue damage in chronic metabolic and inflammatory diseases. In human subjects, multiple reports suggest that in the plasma/serum, circulating levels of distinct forms of soluble RAGEs may be biomarkers of the presence or absence, and the extent of chronic disease. These considerations prompt us to consider in this review, what are soluble RAGEs; how are they formed; what might be their natural functions; and may they serve as biomarkers of inflammatory and metabolic disease activity? In this brief review, we seek to address what is known and suggest new areas for scientific investigation to uncover the biology of soluble RAGEs.

Entities: CellLine Chemical Disease Gene Species

Keywords: Soluble RAGE

Mesh：

Substances：

Year: 2015 PMID： 26130225 PMCID： PMC4547874 DOI： 10.1016/j.vph.2015.06.011

Source DB: PubMed Journal: Vascul Pharmacol ISSN： 1537-1891 Impact factor: 5.773

68 in total

1. The receptor for advanced glycation end products is induced by the glycation products themselves and tumor necrosis factor-alpha through nuclear factor-kappa B, and by 17beta-estradiol through Sp-1 in human vascular endothelial cells.

Authors: N Tanaka; H Yonekura; S Yamagishi; H Fujimori; Y Yamamoto; H Yamamoto
Journal: J Biol Chem Date: 2000-08-18 Impact factor: 5.157

Review 2. Emerging Targets for Therapeutic Development in Diabetes and Its Complications: The RAGE Signaling Pathway.

Authors: Ems Litwinoff; C Hurtado Del Pozo; R Ramasamy; A M Schmidt
Journal: Clin Pharmacol Ther Date: 2015-06-25 Impact factor: 6.875

3. The soluble form of the receptor of advanced glycation endproducts increases after bariatric surgery in morbid obesity.

Authors: J M Brix; F Höllerl; H-P Kopp; G H Schernthaner; G Schernthaner
Journal: Int J Obes (Lond) Date: 2012-07-17 Impact factor: 5.095

4. Circulating levels of soluble receptor for advanced glycation end products in Alzheimer disease and vascular dementia.

Authors: Enzo Emanuele; Angela D'Angelo; Carmine Tomaino; Giuliano Binetti; Roberta Ghidoni; Pierluigi Politi; Livia Bernardi; Raffaele Maletta; Amalia C Bruni; Diego Geroldi
Journal: Arch Neurol Date: 2005-11

5. Plasma levels of soluble receptor for advanced glycation end products and coronary artery disease in nondiabetic men.

Authors: Colomba Falcone; Enzo Emanuele; Angela D'Angelo; Maria P Buzzi; Chiara Belvito; Mariaclara Cuccia; Diego Geroldi
Journal: Arterioscler Thromb Vasc Biol Date: 2005-02-24 Impact factor: 8.311

6. Calcitriol treatment increases serum levels of the soluble receptor of advanced glycation end products in hemodialysis patients with secondary hyperparathyroidism.

Authors: Ji Yoon Sung; Wookyung Chung; Ae Jin Kim; Hyung Soo Kim; Han Ro; Jae Hyun Chang; Hyun Hee Lee; Ji Yong Jung
Journal: Tohoku J Exp Med Date: 2013-05 Impact factor: 1.848

7. Soluble receptors for advanced glycation end products (sRAGE) as a predictor of restenosis following percutaneous coronary intervention.

Authors: Erick D McNair; Calvin R Wells; A Mabood Qureshi; Rashpal Basran; Colin Pearce; Jason Orvold; Jacobus Devilliers; Kailash Prasad
Journal: Clin Cardiol Date: 2010-11 Impact factor: 2.882

8. Thiazolidinedione increases serum soluble receptor for advanced glycation end-products in type 2 diabetes.

Authors: K C B Tan; W S Chow; A W K Tso; A Xu; H F Tse; R L C Hoo; D J Betteridge; K S L Lam
Journal: Diabetologia Date: 2007-07-18 Impact factor: 10.122

9. The decrease of soluble RAGE levels in rheumatoid arthritis patients following hormone replacement therapy is associated with increased bone mineral density and diminished bone/cartilage turnover: a randomized controlled trial.

Authors: Rille Pullerits; Helena Forsblad d'Elia; Andrej Tarkowski; Hans Carlsten
Journal: Rheumatology (Oxford) Date: 2009-05-04 Impact factor: 7.580

10. The presence of high mobility group box-1 and soluble receptor for advanced glycation end-products in juvenile idiopathic arthritis and juvenile systemic lupus erythematosus.

Authors: Dubravka Bobek; Danka Grčević; Nataša Kovačić; Ivan Krešimir Lukić; Marija Jelušić
Journal: Pediatr Rheumatol Online J Date: 2014-12-03 Impact factor: 3.054

38 in total

1. Racial differences in circulating levels of the soluble receptor for advanced glycation endproducts in middle-aged and older adults.

Authors: Tina E Brinkley; Xiaoyan Leng; Barbara J Nicklas; Stephen B Kritchevsky; Jingzhong Ding; Dalane W Kitzman; W Gregory Hundley
Journal: Metabolism Date: 2017-02-10 Impact factor: 8.694

Review 2. Implication of advanced glycation end products (Ages) and their receptor (Rage) on myocardial contractile and mitochondrial functions.

Authors: Remi Neviere; Yichi Yu; Lei Wang; Frederic Tessier; Eric Boulanger
Journal: Glycoconj J Date: 2016-06-08 Impact factor: 2.916

Review 3. Cellular mechanisms and consequences of glycation in atherosclerosis and obesity.

Authors: Raquel López-Díez; Alexander Shekhtman; Ravichandran Ramasamy; Ann Marie Schmidt
Journal: Biochim Biophys Acta Date: 2016-05-08

4. Short-term pharmacologic RAGE inhibition differentially affects bone and skeletal muscle in middle-aged mice.

Authors: Hannah M Davis; Alyson L Essex; Sinai Valdez; Padmini J Deosthale; Mohammad W Aref; Matthew R Allen; Andrea Bonetto; Lilian I Plotkin
Journal: Bone Date: 2019-04-24 Impact factor: 4.398

5. Correlation between follicular fluid levels of sRAGE and vitamin D in women with PCOS.

Authors: Deepika Garg; Richard Grazi; Geralyn M Lambert-Messerlian; Zaher Merhi
Journal: J Assist Reprod Genet Date: 2017-08-19 Impact factor: 3.412

6. Multiomics of World Trade Center Particulate Matter-induced Persistent Airway Hyperreactivity. Role of Receptor for Advanced Glycation End Products.

Authors: Syed H Haider; Arul Veerappan; George Crowley; Erin J Caraher; Dean Ostrofsky; Mena Mikhail; Rachel Lam; Yuyan Wang; Maria Sunseri; Sophia Kwon; David J Prezant; Mengling Liu; Ann Marie Schmidt; Anna Nolan
Journal: Am J Respir Cell Mol Biol Date: 2020-08 Impact factor: 6.914

Review 7. 22016 ATVB Plenary Lecture: Receptor for Advanced Glycation Endproducts and Implications for the Pathogenesis and Treatment of Cardiometabolic Disorders: Spotlight on the Macrophage.

Authors: Ann Marie Schmidt
Journal: Arterioscler Thromb Vasc Biol Date: 2017-02-09 Impact factor: 8.311

8. Correlations between Photodegradation of Bisretinoid Constituents of Retina and Dicarbonyl Adduct Deposition.

Authors: Jilin Zhou; Keiko Ueda; Jin Zhao; Janet R Sparrow
Journal: J Biol Chem Date: 2015-09-22 Impact factor: 5.157

Review 9. Glycation & the RAGE axis: targeting signal transduction through DIAPH1.

Authors: Alexander Shekhtman; Ravichandran Ramasamy; Ann Marie Schmidt
Journal: Expert Rev Proteomics Date: 2016-12-22 Impact factor: 3.940

10. Osteoblasts remotely supply lung tumors with cancer-promoting SiglecF^high neutrophils.

Authors: Camilla Engblom; Christina Pfirschke; Rapolas Zilionis; Janaina Da Silva Martins; Stijn A Bos; Gabriel Courties; Steffen Rickelt; Nicolas Severe; Ninib Baryawno; Julien Faget; Virginia Savova; David Zemmour; Jaclyn Kline; Marie Siwicki; Christopher Garris; Ferdinando Pucci; Hsin-Wei Liao; Yi-Jang Lin; Andita Newton; Omar K Yaghi; Yoshiko Iwamoto; Benoit Tricot; Gregory R Wojtkiewicz; Matthias Nahrendorf; Virna Cortez-Retamozo; Etienne Meylan; Richard O Hynes; Marie Demay; Allon Klein; Miriam A Bredella; David T Scadden; Ralph Weissleder; Mikael J Pittet
Journal: Science Date: 2017-12-01 Impact factor: 47.728