Literature DB >> 26129944

netview p: a network visualization tool to unravel complex population structure using genome-wide SNPs.

Eike J Steinig1, Markus Neuditschko2, Mehar S Khatkar2,3, Herman W Raadsma1,2,3, Kyall R Zenger1,3.   

Abstract

Network-based approaches are emerging as valuable tools for the analysis of complex genetic structure in wild and captive populations. netview p combines data quality control with the construction of population networks through mutual k-nearest neighbours thresholds applied to genome-wide SNPs. The program is cross-platform compatible, open-source and efficiently operates on data ranging from hundreds to hundreds of thousands of SNPs. The pipeline was used for the analysis of pedigree data from simulated (n = 750, SNPs = 1279) and captive silver-lipped pearl oysters (n = 415, SNPs = 1107), wild populations of the European hake from the Atlantic and Mediterranean (n = 834, SNPs = 380) and grey wolves from North America (n = 239, SNPs = 78 255). The population networks effectively visualize large- and fine-scale genetic structure within and between populations, including family-level structure and relationships. netview p comprises a network-based addition to other population analysis tools and provides user-friendly access to a complex network analysis pipeline through implementation in python.
© 2015 John Wiley & Sons Ltd.

Entities:  

Keywords:  SNP; graph theory; netview; network analysis; population genetics; wild and captive populations

Mesh:

Year:  2015        PMID: 26129944     DOI: 10.1111/1755-0998.12442

Source DB:  PubMed          Journal:  Mol Ecol Resour        ISSN: 1755-098X            Impact factor:   7.090


  35 in total

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3.  The Significance of PCR Primer Design in Genetic Diversity Studies: Exemplified by Recent Research into the Genetic Structure of Marine Species.

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6.  A Parallel Population Genomic and Hydrodynamic Approach to Fishery Management of Highly-Dispersive Marine Invertebrates: The Case of the Fijian Black-Lip Pearl Oyster Pinctada margaritifera.

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7.  Infection dynamics, dispersal, and adaptation: understanding the lack of recovery in a remnant frog population following a disease outbreak.

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9.  Ethiopian indigenous goats offer insights into past and recent demographic dynamics and local adaptation in sub-Saharan African goats.

Authors:  Getinet M Tarekegn; Negar Khayatzadeh; Bin Liu; Sarah Osama; Aynalem Haile; Barbara Rischkowsky; Wenguang Zhang; Kassahun Tesfaye; Tadelle Dessie; Okeyo A Mwai; Appolinaire Djikeng; Joram M Mwacharo
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10.  Genome-Wide SNP Discovery, Genotyping and Their Preliminary Applications for Population Genetic Inference in Spotted Sea Bass (Lateolabrax maculatus).

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