Literature DB >> 2612879

Assimilation of methylamine by Paracoccus denitrificans involves formaldehyde transport by a specific carrier.

M Köstler1, D Kleiner.   

Abstract

Assimilation of methylamine by Paracoccus denitrificans involves the following enzymes: a periplasmic methylamine dehydrogenase, a formaldehyde transport system, cytoplasmic formaldehyde and formate dehydrogenase. Formaldehyde transport follows saturation kinetics with a high substrate affinity (Km = 7 microM), and is severely inhibited by iodoacetate, cyanide and p-trifluoromethoxy carbonylcyanide phenylhydrazone. Expression of the formaldehyde carrier is regulated by the carbon source.

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Year:  1989        PMID： 2612879     DOI： 10.1016/0378-1097(89)90356-x

Source DB:  PubMed          Journal:  FEMS Microbiol Lett        ISSN： 0378-1097            Impact factor:   2.742


  4 in total

Review 1.  C1 metabolism in Paracoccus denitrificans: genetics of Paracoccus denitrificans.

Authors:  N Harms; R J van Spanning
Journal:  J Bioenerg Biomembr       Date:  1991-04       Impact factor: 2.945

2.  S-formylglutathione hydrolase of Paracoccus denitrificans is homologous to human esterase D: a universal pathway for formaldehyde detoxification?

Authors:  N Harms; J Ras; W N Reijnders; R J van Spanning; A H Stouthamer
Journal:  J Bacteriol       Date:  1996-11       Impact factor: 3.490

Review 3.  Molecular genetics of the genus Paracoccus: metabolically versatile bacteria with bioenergetic flexibility.

Authors:  S C Baker; S J Ferguson; B Ludwig; M D Page; O M Richter; R J van Spanning
Journal:  Microbiol Mol Biol Rev       Date:  1998-12       Impact factor: 11.056

4.  Isolation, sequencing, and mutagenesis of the gene encoding NAD- and glutathione-dependent formaldehyde dehydrogenase (GD-FALDH) from Paracoccus denitrificans, in which GD-FALDH is essential for methylotrophic growth.

Authors:  J Ras; P W Van Ophem; W N Reijnders; R J Van Spanning; J A Duine; A H Stouthamer; N Harms
Journal:  J Bacteriol       Date:  1995-01       Impact factor: 3.490
  4 in total

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