[Changes in the spreading depression wave in rats in the postresuscitation period].

Functional state of the rat brain cortex after a 10-minute arrest of blood circulation was studied by means of the spreading depression wave, the latter leading to significant energy expenditures and being accompanied by a transmitter output and changes in extra- and intracellular ion concentration. The changes in the spreading depression wave took place at different stages of the postresuscitation period (2 hours to 2 1/2 months), suggesting various pathological changes in functional state of the brain cortex induced by disturbances in neurological interrelationships.