Literature DB >> 26126276

Aneuploidy.

Bernardo Orr1, Kristina M Godek1, Duane Compton2.   

Abstract

The terms 'haploid' and 'diploid' that describe single (n) and double (2n) chromosome sets in cells were coined by the Polish-German botanist Eduard Strasburger and originate from the Greek terms haplóos meaning 'single' and diplóos meaning 'double'. The term 'ploidy' was subsequently derived to describe the total chromosome content of cells. Consequently, the term 'euploid' refers to a chromosome complement that is an exact multiple of the haploid number. Therefore, haploids and diploids are both cases of normal euploidy. Euploid types that have more than two sets of chromosomes are 'polyploid' such as 'triploid' (3n), 'tetraploid' (4n), 'pentaploid' (5n), and so forth. There are various natural euploid states with some organisms existing as haploids (fungi), diploids (most mammals), and polyploids (plants).
Copyright © 2015 Elsevier Ltd. All rights reserved.

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Year:  2015        PMID： 26126276      PMCID： PMC4714037          DOI： 10.1016/j.cub.2015.05.010

Source DB:  PubMed          Journal:  Curr Biol        ISSN： 0960-9822            Impact factor:   10.834


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4.  Proliferation of aneuploid human cells is limited by a p53-dependent mechanism.

Authors:  Sarah L Thompson; Duane A Compton
Journal:  J Cell Biol       Date:  2010-02-01       Impact factor: 10.539

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Journal:  Nature       Date:  2010-10-20       Impact factor: 49.962

6.  Effects of aneuploidy on cellular physiology and cell division in haploid yeast.

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Journal:  J Cell Biol       Date:  2008-02-18       Impact factor: 10.539
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6.  Single-cell RNA sequencing reveals the impact of chromosomal instability on glioblastoma cancer stem cells.

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10.  The Phenoxyphenol Compound 4-HPPP Selectively Induces Antiproliferation Effects and Apoptosis in Human Lung Cancer Cells through Aneupolyploidization and ATR DNA Repair Signaling.

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