Literature DB >> 2612506

Fatal infectious mononucleosis with staphylococcal pyoderma in a girl with hereditary immunological dysregulations.

T Inaba1, R Hanada, A Yaginuma, Y Hayashi, K Yamamoto, H Hukada.   

Abstract

We describe a 14-year-old girl with fatal infectious mononucleosis with high fever, pancytopenia, and multiple skin ulcers due to Staphylococcus aureus. Immunological studies revealed low serum IgM, low natural killer (NK) activity, and high CD4/CD8 ratio. Her father had also low NK activity and high CD4/CD8 ratio. It is suggested that she had a dominantly inherited immunodeficiency predisposing to severe Epstein-Barr virus infection.

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Year:  1989        PMID: 2612506     DOI: 10.1007/bf01958275

Source DB:  PubMed          Journal:  Eur J Pediatr        ISSN: 0340-6199            Impact factor:   3.183


  5 in total

1.  Fatal infectious mononucleosis and virus-associated hemophagocytic syndrome.

Authors:  E C Mroczek; D D Weisenburger; H L Grierson; R Markin; D T Purtilo
Journal:  Arch Pathol Lab Med       Date:  1987-06       Impact factor: 5.534

2.  A non-x-linked syndrome with susceptibility to severe Epstein-Barr virus infections.

Authors:  G Fleisher; S Starr; N Koven; H Kamiya; S D Douglas; W Henle
Journal:  J Pediatr       Date:  1982-05       Impact factor: 4.406

3.  Selective immunoglobulin M (IgM) deficiency in two immunodeficient adults with recurrent staphylococcal pyoderma.

Authors:  M W Yocum; D M Strong; M J Chusid; J D Lakin
Journal:  Am J Med       Date:  1976-04       Impact factor: 4.965

4.  X-linked recessive progressive combined variable immunodeficiency (Duncan's disease).

Authors:  D T Purtilo; C K Cassel; J P Yang; R Harper
Journal:  Lancet       Date:  1975-04-26       Impact factor: 79.321

5.  A familial syndrome of susceptibility to chronic active Epstein-Barr virus infection.

Authors:  J H Joncas; F Ghibu; M Blagdon; S Montplaisir; I Stefanescu; J Menezes
Journal:  Can Med Assoc J       Date:  1984-02-01       Impact factor: 8.262

  5 in total
  1 in total

Review 1.  Epstein-Barr virus infection and associated diseases in children. I. Pathogenesis, epidemiology and clinical aspects.

Authors:  V Schuster; H W Kreth
Journal:  Eur J Pediatr       Date:  1992-10       Impact factor: 3.183

  1 in total

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