Literature DB >> 2612502

Osteonecrosis of vertebrae in a child with acute lymphocytic leukaemia during L-asparaginase therapy.

T Hanada1, Y Horigome, M Inudoh, H Takita.   

Abstract

We report a child with acute lymphocytic leukaemia who developed simultaneous osteonecrosis of vertebrae and cerebral thrombosis during L-asparaginase therapy. Fibrinogen, antithrombin III and plasminogen were decreased. Fresh frozen plasma in addition to antithrombin III concentrates were used to replenish these haemostatic proteins. L-asparaginase induced coagulopathy may cause osteonecrosis.

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Year:  1989        PMID： 2612502     DOI： 10.1007/bf01958270

Source DB:  PubMed          Journal:  Eur J Pediatr        ISSN： 0340-6199            Impact factor:   3.183


  9 in total

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3.  Thromboembolic complications associated with L-asparaginase therapy. Etiologic role of low antithrombin III and plasminogen levels and therapeutic correction by fresh frozen plasma.

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Journal:  Cancer       Date:  1985-02-15       Impact factor: 6.860

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Journal:  Eur J Pediatr       Date:  1982-09       Impact factor: 3.183

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6.  Avascular necrosis of bone following combination chemotherapy for acute lymphocytic leukemia.

Authors:  C Felix; J Blatt; M A Goodman; J Medina
Journal:  Med Pediatr Oncol       Date:  1985

Review 7.  Cerebrovascular complications of L-asparaginase therapy.

Authors:  W M Feinberg; M R Swenson
Journal:  Neurology       Date:  1988-01       Impact factor: 9.910

8.  Avascular necrosis of bone caused by combination chemotherapy without corticosteroids.

Authors:  P G Harper; C Trask; R L Souhami
Journal:  Br Med J (Clin Res Ed)       Date:  1984-01-28

9.  Four-agent induction and intensive asparaginase therapy for treatment of childhood acute lymphoblastic leukemia.

Authors:  L A Clavell; R D Gelber; H J Cohen; S Hitchcock-Bryan; J R Cassady; N J Tarbell; S R Blattner; R Tantravahi; P Leavitt; S E Sallan
Journal:  N Engl J Med       Date:  1986-09-11       Impact factor: 91.245
  9 in total
  10 in total

1.  Clinical utility and implications of asparaginase antibodies in acute lymphoblastic leukemia.

Authors:  C Liu; J D Kawedia; C Cheng; D Pei; C A Fernandez; X Cai; K R Crews; S C Kaste; J C Panetta; W P Bowman; S Jeha; J T Sandlund; W E Evans; C-H Pui; M V Relling
Journal:  Leukemia       Date:  2012-04-09       Impact factor: 11.528

Review 2.  Role of genetic susceptibility in development of treatment-related adverse outcomes in cancer survivors.

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Authors:  Marina Kunstreich; Sebastian Kummer; Hans-Juergen Laws; Arndt Borkhardt; Michaela Kuhlen
Journal:  Haematologica       Date:  2016-10-14       Impact factor: 9.941

4.  Cell-cycle inhibition by Helicobacter pylori L-asparaginase.

Authors:  Claudia Scotti; Patrizia Sommi; Maria Valentina Pasquetto; Donata Cappelletti; Simona Stivala; Paola Mignosi; Monica Savio; Laurent Roberto Chiarelli; Giovanna Valentini; Victor M Bolanos-Garcia; Douglas Scott Merrell; Silvia Franchini; Maria Luisa Verona; Cristina Bolis; Enrico Solcia; Rachele Manca; Diego Franciotta; Andrea Casasco; Paola Filipazzi; Elisabetta Zardini; Vanio Vannini
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6.  [Osteonecrosis after chemotherapy in children].

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7.  Symptomatic osteonecrosis in childhood leukemia survivors: prevalence, risk factors and impact on quality of life in adulthood.

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8.  Asparaginase Potentiates Glucocorticoid-Induced Osteonecrosis in a Mouse Model.

Authors:  Chengcheng Liu; Laura J Janke; Jitesh D Kawedia; Laura B Ramsey; Xiangjun Cai; Leonard A Mattano; Kelli L Boyd; Amy J Funk; Mary V Relling
Journal:  PLoS One       Date:  2016-03-11       Impact factor: 3.240

9.  British OsteoNEcrosis Study (BONES) protocol: a prospective cohort study to examine the natural history of osteonecrosis in older children, teenagers and young adults with acute lymphoblastic leukaemia and lymphoblastic lymphoma.

Authors:  Nadia Amin; Sally Kinsey; Richard Feltbower; Jeannette Kraft; Elizabeth Whitehead; Mark Velangi; Beki James
Journal:  BMJ Open       Date:  2019-05-22       Impact factor: 2.692

10.  Osteonecrosis in patients with acute lymphoblastic leukaemia: a national questionnaire study.

Authors:  Nadia Laila Amin; Richard Feltbower; Sally Kinsey; Ajay Vora; Beki James
Journal:  BMJ Paediatr Open       Date:  2017-09-11
  10 in total

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