Literature DB >> 26123734

Three-dimensional analysis of maxillary development in patients with unilateral cleft lip and palate during the first six years of life.

Nadezhda Stancheva1, Karl-Heinz Dannhauer1, Alexander Hemprich2, Karl-Friedrich Krey3.   

Abstract

OBJECTIVES: The purpose of this work was to analyse early upper-jaw development in patients with unilateral cleft lip and palate (UCLP) treated using two different concepts and to compare shape and size developments between these two groups and a group of noncleft patients.
MATERIALS AND METHODS: A total of 204 maxillary casts available for this study from 50 UCLP patients were analyzed for upper-jaw development based on three-dimensional measurements performed with a Reflex Microscope from birth up to 71 months of age. Thirty-five of these 50 patients were part of an early treatment group (two-stage cleft closure with single-stage palatoplasty at an age of 10-14 months) and 15 were part of a late treatment group (two-stage cleft closure with palatoplasty at an age of 4-7 years). The control group included 39 casts of 17 noncleft patients.
RESULTS: Analysis of shape and size between the patients in the three groups yielded statistically significant differences between the cleft and the noncleft patients. In both treatment groups, we made observations typically associated with cleft formation like lateralization, asymmetry of the greater and lesser cleft segments, and pronounced vertical deviations of the segments. Viewed in all dimensions, however, the patients in the early treatment group approached the control group more closely, although a statistically significant difference was still observed.
CONCLUSION: Our results suggest that the timing of hard-palate closure is not a decisive factor for upper-jaw development. Intrinsic factors (initial cleft width, presence of tooth buds) and the surgeon's skills appear to have a much more defining role.

Entities:  

Keywords:  3D measurement; Reflex microscope; Treatment concept; Unilateral cleft lip and palate

Mesh:

Year:  2015        PMID: 26123734     DOI: 10.1007/s00056-015-0299-z

Source DB:  PubMed          Journal:  J Orofac Orthop        ISSN: 1434-5293            Impact factor:   1.938


  34 in total

1.  Dental arch relationship outcomes in children with complete unilateral cleft lip and palate treated at Princess Margaret Hospital for Children, Perth, Western Australia.

Authors:  Robert Love; Mark Walters; Peter Southall; Steve Singer; David Gillett
Journal:  Cleft Palate Craniofac J       Date:  2011-01-27

2.  A six-center international study of treatment outcome in patients with clefts of the lip and palate: Part 5. General discussion and conclusions.

Authors:  W C Shaw; E Dahl; C Asher-McDade; V Brattström; M Mars; J McWilliam; K Mølsted; D A Plint; B Prahl-Andersen; C Roberts
Journal:  Cleft Palate Craniofac J       Date:  1992-09

3.  Three-dimensional measurement: the accuracy and precision of the Reflex Microscope.

Authors:  B Speculand; G W Butcher; C D Stephens
Journal:  Br J Oral Maxillofac Surg       Date:  1988-08       Impact factor: 1.651

4.  Presurgical orthopedics has no effect on archform in unilateral cleft lip and palate.

Authors:  Nazan Adali; Michael Mars; Aviva Petrie; Joe Noar; Brian Sommerlad
Journal:  Cleft Palate Craniofac J       Date:  2011-08-08

5.  Long-term evidence for favorable midfacial growth after delayed hard palate repair in UCLP patients.

Authors:  H Friede; H Enemark
Journal:  Cleft Palate Craniofac J       Date:  2001-07

Review 6.  Treatment outcome in cleft lip and palate: issues and perspectives.

Authors:  K Mølsted
Journal:  Crit Rev Oral Biol Med       Date:  1999

7.  [3-D model analysis of the maxilla of infants with lip-jaw-palate clefts].

Authors:  B Braumann; L Keilig; C Bourauel; A Jäger
Journal:  Biomed Tech (Berl)       Date:  1999-11       Impact factor: 1.411

8.  Investigations on the palatal rugae pattern in cleft patients. Part I: A morphological analysis.

Authors:  H Kratzsch; C Opitz
Journal:  J Orofac Orthop       Date:  2000       Impact factor: 1.938

9.  Three-dimensional geometric morphometrics applied to the study of children with cleft lip and/or palate from the North East of England.

Authors:  I Bugaighis; P O'Higgins; B Tiddeman; C Mattick; O Ben Ali; R Hobson
Journal:  Eur J Orthod       Date:  2010-01-22       Impact factor: 3.075

10.  Dental arch dimensions in patients with unilateral cleft lip and palate.

Authors:  A E Athanasiou; M Mazaheri; K Zarrinnia
Journal:  Cleft Palate J       Date:  1988-04
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  1 in total

1.  Three-dimensional morphology of first molars in relation to ethnicity and the occurrence of cleft lip and palate.

Authors:  Sandra Echtermeyer; Philine H Metelmann; Alexander Hemprich; Karl-Heinz Dannhauer; Karl-Friedrich Krey
Journal:  PLoS One       Date:  2017-10-09       Impact factor: 3.240

  1 in total

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