| Literature DB >> 26121554 |
Mathéo Berthet1, Florian Davanier1, Gilles Dujardin2, Jean Martinez1, Isabelle Parrot3.
Abstract
The scope of MgI2 as a valuable tool for quantitative and mild chemoselective cleavage of protecting groups is described here. This novel synthetic approach expands the use of protecting groups, widens the concept of orthogonality in synthetic processes, and offers a facile opportunity to release compounds from solid supports.Keywords: carbamates; cleavage reactions; esters; protecting groups; solid-phase synthesis
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Year: 2015 PMID: 26121554 DOI: 10.1002/chem.201501799
Source DB: PubMed Journal: Chemistry ISSN: 0947-6539 Impact factor: 5.236