Literature DB >> 26118663

Management of CNS germinoma.

Diana S Osorio1,2, Jeffrey C Allen1.   

Abstract

The following is a general overview of the management of CNS germinomas. Over the last 35 years, CNS germinomas have become one of the pediatric brain tumors with the best outcomes with a greater than 85% overall survival over 5 years. This is in part due to the fact that germinomas are very responsive to chemotherapy and radiation. Some of the major challenges going forward will be to find ways to minimize the adverse effects of our treatments particularly with regard to radiation and to improve the quality of life of patients who develop neurologic, neurocognitive and/or endocrine deficiencies.

Entities:  

Keywords:  BHCG; CNS; brain tumor; chemotherapy; germ cell tumor; germinoma; management; pediatric; pure germinoma; radiation

Mesh：

Year:  2015        PMID： 26118663      PMCID： PMC6088312          DOI： 10.2217/cns.15.13

Source DB:  PubMed          Journal:  CNS Oncol        ISSN： 2045-0907


  34 in total

1.  Pure pineal germinomas: analysis of gender incidence.

Authors:  V Cuccia; M Galarza
Journal:  Acta Neurochir (Wien)       Date:  2006-06-23       Impact factor: 2.216

2.  C-kit gene mutation: common and widely distributed in intracranial germinomas.

Authors:  Yayoi Kamakura; Mitsuhiro Hasegawa; Toshinari Minamoto; Junkoh Yamashita; Hironori Fujisawa
Journal:  J Neurosurg       Date:  2006-03       Impact factor: 5.115

Review 3.  Update on current standard treatments in central nervous system germ cell tumors.

Authors:  Yuuta Kamoshima; Yutaka Sawamura
Journal:  Curr Opin Neurol       Date:  2010-12       Impact factor: 5.710

4.  Nonmetastatic intracranial germinoma: the experience of the French Society of Pediatric Oncology.

Authors:  M C Baranzelli; C Patte; E Bouffet; D Couanet; J L Habrand; M Portas; O Lejars; P Lutz; E Le Gall; C Kalifa
Journal:  Cancer       Date:  1997-11-01       Impact factor: 6.860

5.  Induction chemotherapy followed by reduced-volume radiation therapy for newly diagnosed central nervous system germinoma.

Authors:  Y Sawamura; H Shirato; J Ikeda; M Tada; N Ishii; T Kato; H Abe; K Fujieda
Journal:  J Neurosurg       Date:  1998-01       Impact factor: 5.115

Review 6.  A review of soluble c-kit (s-kit) as a novel tumor marker and possible molecular target for the treatment of CNS germinoma.

Authors:  Hideo Takeshima; Jun-Ichi Kuratsu
Journal:  Surg Neurol       Date:  2003-10

Review 7.  Intracranial germ-cell tumors: natural history and pathogenesis.

Authors:  M T Jennings; R Gelman; F Hochberg
Journal:  J Neurosurg       Date:  1985-08       Impact factor: 5.115

8.  Intracranial germ cell tumors: association with Klinefelter syndrome and sex chromosome aneuploidies.

Authors:  G Queipo; D Aguirre; K Nieto; Y R Peña; I Palma; J Olvera; L Chavez; N Nájera; S Kofman-Alfaro
Journal:  Cytogenet Genome Res       Date:  2008-08-28       Impact factor: 1.636

9.  Potential role of ventricular tumor markers in CNS germ cell tumors.

Authors:  Geneviève Legault; Jeffrey C Allen
Journal:  Pediatr Blood Cancer       Date:  2013-06-20       Impact factor: 3.167

10.  Combined treatment modality for intracranial germinomas: results of a multicentre SFOP experience. Société Française d'Oncologie Pédiatrique.

Authors:  E Bouffet; M C Baranzelli; C Patte; M Portas; C Edan; P Chastagner; F Mechinaud-Lacroix; C Kalifa
Journal:  Br J Cancer       Date:  1999-03       Impact factor: 7.640
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  14 in total

1.  Balanced Steady-State Free Precession Techniques Improve Detection of Residual Germ Cell Tumor for Treatment Planning.

Authors:  W A Mehan; K Buch; M F Brasz; F F J Simonis; S MacDonald; S Rincon; J E Kirsch; P Caruso
Journal:  AJNR Am J Neuroradiol       Date:  2020-04-30       Impact factor: 3.825

2.  Treatment Outcome of a β-hCG Secreting Intracranial Germ Cell Tumor in an Adult Filipino Using Definitive Chemotherapy Followed by Radiotherapy: A Case Report.

Authors:  Florence Rochelle Gan; Maria Honolina Gomez; Julie Ann Tapispisan
Journal:  J ASEAN Fed Endocr Soc       Date:  2022-05-13

3.  Primary cranial vault germinoma in a 23-year-old man: illustrative case.

Authors:  Christopher Lauren; Donny Argie; Elric B Malelak; Reza Mawardy; Samuel E Suranta; Vito M Junaidy; Yohanes Firmansyah
Journal:  J Neurosurg Case Lessons       Date:  2021-04-05

4.  Co-existence of multiple sclerosis and germinoma in an adult male: Case report.

Authors:  Jan Bian; Alison Westrup; Sarah Sung; Nidhiben A Anadani; Kar-Ming Fung; Andrew K Conner
Journal:  Surg Neurol Int       Date:  2021-04-19

5.  Bifocal germinoma in a patient with 16p11.2 microdeletion syndrome.

Authors:  Mara Ventura; Leonor Gomes; Joana Rosmaninho-Salgado; Luísa Barros; Isabel Paiva; Miguel Melo; Diana Oliveira; Francisco Carrilho
Journal:  Endocrinol Diabetes Metab Case Rep       Date:  2019-02-07

6.  Value of C-11 methionine PET/CT in patients with intracranial germinoma.

Authors:  Yong-Jin Park; Ji Won Lee; Hee Won Cho; Yearn Seong Choe; Kyung-Han Lee; Joon Young Choi; Ki Woong Sung; Seung Hwan Moon
Journal:  PLoS One       Date:  2022-02-07       Impact factor: 3.240

7.  Rate of radiation-induced microbleed formation on 7T MRI relates to cognitive impairment in young patients treated with radiation therapy for a brain tumor.

Authors:  Melanie A Morrison; Sabine Mueller; Erin Felton; Angela Jakary; Schuyler Stoller; Sivakami Avadiappan; Justin Yuan; Annette M Molinaro; Steve Braunstein; Anu Banerjee; Christopher P Hess; Janine M Lupo
Journal:  Radiother Oncol       Date:  2020-09-20       Impact factor: 6.280

8.  Central diabetes insipidus caused by a pituitary stalk germinoma resembling infundibuloneurohypophysitis.

Authors:  Daniela Dias; Helena Vilar; João Passos; Valeriano Leite
Journal:  BMJ Case Rep       Date:  2020-09-09

9.  PD-1/PD-L1 expression in a series of intracranial germinoma and its association with Foxp3+ and CD8+ infiltrating lymphocytes.

Authors:  Bin Liu; Yoshiki Arakawa; Ryuta Yokogawa; Shinya Tokunaga; Yukinori Terada; Daiki Murata; Yasuzumi Matsui; Ko-Ichi Fujimoto; Nobuyuki Fukui; Masahiro Tanji; Yohei Mineharu; Sachiko Minamiguchi; Susumu Miyamoto
Journal:  PLoS One       Date:  2018-04-04       Impact factor: 3.240

10.  Endoscopic Transsphenoidal Approach in Treatment of Germinomas of the Chiasmosellar Region.

Authors:  Maxim Alexandrovich Kutin; Dmitry Vladislavovich Fomichev; Alexey Nikolaevich Shkarubo; Ilia Valerievich Chernov; Oleg Ildarovich Sharipov; Dmitry Nikolaevich Andreev; Denilbek Beksultanovich Ismailov; Nikita Igorevich Mikhailov; Grigoriy Lvovich Kobyakov; Yuriy Yurievich Trunin; Ludmila Igorevna Astafyeva; Abdishukur Abdilatipovich Abdilatipov; Artem Andreevich Poddubsky; Pavel Lvovich Kalinin
Journal:  Asian J Neurosurg       Date:  2019-11-25
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