Literature DB >> 26118638

Outpatient medical abortion is safe and effective through 70 days gestation.

Dina Abbas1, Erica Chong2, Elizabeth G Raymond2.   

Abstract

Data show that an outpatient regimen of 200-mg mifepristone followed by a single dose of misoprostol is safe and effective for medical abortion for up to 70 days from last menstrual period (LMP). Yet, many clinics only provide services up to 63 days LMP, and some practice guidelines do not recommend the higher gestational age limit. We review the studies published to date that include women 64 to 70 days LMP and conclude that outpatient medical abortion is safe and effective in this interval and that there are no clinically meaningful differences between outcomes at 57 to 63 days LMP and 64 to 70 days LMP. Updating clinical protocols and revising the Food and Drug administration label for Mifeprex® to change the indication for termination of pregnancies through 70 days LMP will give women more choices and expand access to safe abortion services.
Copyright © 2015 Elsevier Inc. All rights reserved.

Entities:  

Mesh:

Substances:

Year:  2015        PMID: 26118638     DOI: 10.1016/j.contraception.2015.06.018

Source DB:  PubMed          Journal:  Contraception        ISSN: 0010-7824            Impact factor:   3.375


  9 in total

1.  Efficacy of Misoprostol Alone for First-Trimester Medical Abortion: A Systematic Review.

Authors:  Elizabeth G Raymond; Margo S Harrison; Mark A Weaver
Journal:  Obstet Gynecol       Date:  2019-01       Impact factor: 7.661

2.  Comparison of the efficacy of sublingual, oral, and vaginal administration of misoprostol in the medical treatment of missed abortion during first trimester of pregnancy: A randomized clinical trial study.

Authors:  Behnaz Souizi; Rahim Akrami; Fateme Borzoee; Mohammad Sahebkar
Journal:  J Res Med Sci       Date:  2020-07-27       Impact factor: 1.852

Review 3.  Medication to Manage Abortion and Miscarriage.

Authors:  Jessica Beaman; Christine Prifti; Eleanor Bimla Schwarz; Mindy Sobota
Journal:  J Gen Intern Med       Date:  2020-05-14       Impact factor: 5.128

4.  Accuracy of gestational age estimation from last menstrual period among women seeking abortion in South Africa, with a view to task sharing: a mixed methods study.

Authors:  Deborah Constant; Jane Harries; Jennifer Moodley; Landon Myer
Journal:  Reprod Health       Date:  2017-08-22       Impact factor: 3.223

5.  Medical abortion in the late first trimester: a systematic review.

Authors:  Nathalie Kapp; Elisabeth Eckersberger; Antonella Lavelanet; Maria Isabel Rodriguez
Journal:  Contraception       Date:  2018-11-13       Impact factor: 3.375

6.  Commentary: No-test medication abortion: A sample protocol for increasing access during a pandemic and beyond.

Authors:  Elizabeth G Raymond; Daniel Grossman; Alice Mark; Ushma D Upadhyay; Gillian Dean; Mitchell D Creinin; Leah Coplon; Jamila Perritt; Jessica M Atrio; DeShawn Taylor; Marji Gold
Journal:  Contraception       Date:  2020-04-16       Impact factor: 3.375

7.  Medical abortion offered in pharmacy versus clinic-based settings.

Authors:  Maria I Rodriguez; Alison Edelman; Alyssa Hersh; Pragya Gartoulla; Jillian Henderson
Journal:  Cochrane Database Syst Rev       Date:  2021-06-11

8.  Accuracy of Assessment of Eligibility for Early Medical Abortion by Community Health Workers in Ethiopia, India and South Africa.

Authors:  Heidi Bart Johnston; Bela Ganatra; My Huong Nguyen; Ndema Habib; Mesganaw Fantahun Afework; Jane Harries; Kirti Iyengar; Jennifer Moodley; Hailu Yeneneh Lema; Deborah Constant; Swapnaleen Sen
Journal:  PLoS One       Date:  2016-01-05       Impact factor: 3.240

9.  A Retrospective Cost-Effectiveness Analysis of Mifepristone-Misoprostol Medical Abortions in the First Year at the Regina General Hospital.

Authors:  Caitlin Hunter; Joshua Jensen; Biaka Imeah; Michelle McCarron; Megan Clark
Journal:  J Obstet Gynaecol Can       Date:  2020-08-25
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.