Literature DB >> 2611793

Effects of aging on mucociliary clearance.

R A Incalzi1, C L Maini, L Fuso, A Giordano, P U Carbonin, G Galli.   

Abstract

Preliminary results from the relationship between aging and mucociliary clearance of inhaled 99-Tc human albumin particles (0.92-2.5 microns) are reported from two groups of healthy non-smokers: 1) 20-61-year-old (mean 42 years) and 2) 71-90-year-old (mean 79.5 years). The analytical procedure is presented, and on the basis of the analysis it is concluded that there is evidence for an age-related decline of the mucociliary clearance by a bi-phasic curve, similar to those reported in the literature for other physiological functions.

Entities:  

Mesh：

Year:  1989        PMID： 2611793

Source DB:  PubMed          Journal:  Compr Gerontol A        ISSN： 0902-0071


  7 in total

1.  Alcohol potentiates RSV-mediated injury to ciliated airway epithelium.

Authors:  Todd A Wyatt; Kristina L Bailey; Samantha M Simet; Kristi J Warren; Jenea M Sweeter; Jane M DeVasure; Jaqueline A Pavlik; Joseph H Sisson
Journal:  Alcohol       Date:  2018-07-26       Impact factor: 2.405

2.  Reduced mucociliary clearance in old mice is associated with a decrease in Muc5b mucin.

Authors:  Barbara R Grubb; Alessandra Livraghi-Butrico; Troy D Rogers; Weining Yin; Brian Button; Lawrence E Ostrowski
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2016-03-11       Impact factor: 5.464

3.  Cigarette smoke exposure induces CFTR internalization and insolubility, leading to airway surface liquid dehydration.

Authors:  Lucy A Clunes; Catrin M Davies; Raymond D Coakley; Andrei A Aleksandrov; Ashley G Henderson; Kirby L Zeman; Erin N Worthington; Martina Gentzsch; Silvia M Kreda; Deborah Cholon; William D Bennett; John R Riordan; Richard C Boucher; Robert Tarran
Journal:  FASEB J       Date:  2011-10-11       Impact factor: 5.191

4.  Oxidative stress associated with aging activates protein kinase Cε, leading to cilia slowing.

Authors:  Kristina L Bailey; Kusum K Kharbanda; Dawn M Katafiasz; Joseph H Sisson; Todd A Wyatt
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2018-09-13       Impact factor: 5.464

Review 5.  The Impact of Immunosenescence on Pulmonary Disease.

Authors:  Michelle A Murray; Sanjay H Chotirmall
Journal:  Mediators Inflamm       Date:  2015-06-23       Impact factor: 4.711

Review 6.  The role of immunity in susceptibility to respiratory infection in the aging lung.

Authors:  K C Meyer
Journal:  Respir Physiol       Date:  2001-10

7.  Impact of Influenza on Pneumococcal Vaccine Effectiveness during Streptococcus pneumoniae Infection in Aged Murine Lung.

Authors:  Ermias Jirru; Stefi Lee; Rebecca Harris; Jianjun Yang; Soo Jung Cho; Heather Stout-Delgado
Journal:  Vaccines (Basel)       Date:  2020-06-11
  7 in total

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