| Literature DB >> 26117704 |
Thomas Villemonteix1, Stéphane A De Brito2, Hichem Slama3, Martin Kavec4, Danielle Balériaux4, Thierry Metens4, Simon Baijot5, Alison Mary6, Philippe Peigneux7, Isabelle Massat8.
Abstract
Female participants have been underrepresented in previous structural magnetic resonance imaging reports on attention-deficit/hyperactivity disorder (ADHD). In this study, we used optimized voxel-based morphometry to examine grey matter volumes in a sample of 33 never-medicated children with combined-type ADHD and 27 typically developing (TD) children. We found a gender-by-diagnosis interaction effect in the ventral anterior cingulate cortex (ACC), whereby boys with ADHD exhibited reduced volumes compared with TD boys, while girls with ADHD showed increased volumes when compared with TD girls. Considering the key role played by the ventral ACC in emotional regulation, we discuss the potential contribution of these alterations to gender-specific symptoms' profiles in ADHD.Entities:
Keywords: Anterior cingulate cortex; Attention deficit/hyperactivity disorder (ADHD); Emotion regulation; Gender; MRI
Mesh：
Year: 2015 PMID： 26117704 DOI： 10.1016/j.dcn.2015.06.001
Source DB: PubMed Journal: Dev Cogn Neurosci ISSN： 1878-9293 Impact factor: 6.464