| Literature DB >> 26116875 |
Annelies Grimonprez1, Robrecht Raedt2, Chris Baeken3, Paul Boon4, Kristl Vonck5.
Abstract
Vagus nerve stimulation (VNS) is a proposed neuromodulatory treatment for medically refractory major depression. Although VNS is already used in clinical practice, the underlying mechanism of action remains unknown. The present review provides an overview of the preclinical VNS studies in view of two major hypotheses in depression research: the monoaminergic and the neural plasticity hypothesis of depression.Entities:
Keywords: Major depressive disorder; The monoaminergic hypothesis of major depressive disorder; The neural plasticity hypothesis of major depressive disorder; Vagus nerve stimulation
Mesh：
Year: 2015 PMID： 26116875 DOI： 10.1016/j.neubiorev.2015.06.019
Source DB: PubMed Journal: Neurosci Biobehav Rev ISSN： 0149-7634 Impact factor: 8.989