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Literature DB >> 26116735

Antibodies: At The Nexus of Antigens and Cancer Vaccines.

Zenon Steplewski¹, Magdalena Thurin², Thomas Kieber-Emmons³.

Abstract

This review describes the development of monoclonal antibodies and the inception of their use in cancer therapy, their impact on defining cancer biomarkers, and their structural utility in new cancer vaccine development.

Entities: Disease

Keywords: Monoclonal antibodies; anti-idiotypes; biotechnology; cancer therapeutics; cancer vaccines; carbohydrate mimetic peptides; mimicry; team science

Mesh：

Substances：

Year: 2015 PMID： 26116735 PMCID： PMC4490205 DOI： 10.1093/infdis/jiu638

Source DB: PubMed Journal: J Infect Dis ISSN： 0022-1899 Impact factor: 5.226

49 in total

1. Peptide mimicking sialyl-Lewis(a) with anti-inflammatory activity.

Authors: I O; T Kieber-Emmons; L Otvos; M Blaszczyk-Thurin
Journal: Biochem Biophys Res Commun Date: 2000-02-05 Impact factor: 3.575

2. Hybridoma technology: a view from the patent arena.

Authors: P R Ansell
Journal: Immunol Today Date: 2000-08

3. Role of SA-Le(a) and E-selectin in metastasis assessed with peptide antagonist.

Authors: Insug O; Laszlo Otvos; Thomas Kieber-Emmons; Magdalena Blaszczyk-Thurin
Journal: Peptides Date: 2002-05 Impact factor: 3.750

4. Epstein-Barr virus in somatic cell hybrids between mouse cells and human nasopharyngeal carcinoma cells.

Authors: Z Steplewski; H Koprowski; M Andersson-Anvret; G Klein
Journal: J Cell Physiol Date: 1978-10 Impact factor: 6.384

5. The mechanism of internuclear transmission of SV40-induced complement fixation antigen in heterokaryocytes.

Authors: Z Steplewski; B B Knowles; H Koprowski
Journal: Proc Natl Acad Sci U S A Date: 1968-03 Impact factor: 11.205

6. Activation of production of infectious tumor virus SV40 in heterokaryon cultures.

Authors: H Koprowski; F C Jensen; Z Steplewski
Journal: Proc Natl Acad Sci U S A Date: 1967-07 Impact factor: 11.205

7. Reactivity of monoclonal anti-melanoma antibodies with melanoma cells freshly isolated from primary and metastatic melanoma.

Authors: Z Steplewski; M Herlyn; D Herlyn; W H Clark; H Koprowski
Journal: Eur J Immunol Date: 1979-01 Impact factor: 5.532

Antibodies: At The Nexus of Antigens and Cancer Vaccines.

1. Peptide mimicking sialyl-Lewis(a) with anti-inflammatory activity.

2. Hybridoma technology: a view from the patent arena.

3. Role of SA-Le(a) and E-selectin in metastasis assessed with peptide antagonist.

4. Epstein-Barr virus in somatic cell hybrids between mouse cells and human nasopharyngeal carcinoma cells.

5. The mechanism of internuclear transmission of SV40-induced complement fixation antigen in heterokaryocytes.

6. Activation of production of infectious tumor virus SV40 in heterokaryon cultures.

7. Reactivity of monoclonal anti-melanoma antibodies with melanoma cells freshly isolated from primary and metastatic melanoma.

8. Antibodies directed against Lewis-Y antigen inhibit signaling of Lewis-Y modified ErbB receptors.

9. Study of antibodies against human melanoma produced by somatic cell hybrids.

10. A mimic of tumor rejection antigen-associated carbohydrates mediates an antitumor cellular response.

Review 1. Antibody Engineering for Pursuing a Healthier Future.

2. Commentary: Immunology's Coming of Age.

Review 3. Tumor-Associated Glycans as Targets for Immunotherapy: The Wistar Institute Experience/Legacy.