Literature DB >> 2611624

Sperm density measurement: should this be abandoned?

D F Badenoch1, S J Evans, D J McCloskey.   

Abstract

Sperm density measurement by means of the Makler chamber was performed on a single semen specimen from 2 groups: 104 proven fertile men and 53 infertile men; 11.5% of the fertile population had a sperm density less than 20 million/ml (median 84, mean 91.3, SD 60.5) and 33% of the infertile population had a sperm density greater than 20 million/ml (median 10, mean 26.9, SD 34.8). There was a statistically significant difference in median between the 2 groups, but when a discriminant analysis was applied, sperm density could predict fertile status with only 68% accuracy at optimum cut-off. Sperm density is valueless in distinguishing fertile from infertile men and is neither useful in diagnosis nor in monitoring the progress of treatment for male infertility. It should be abandoned as a quotable measurement of male fertility.

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Year:  1989        PMID: 2611624     DOI: 10.1111/j.1464-410x.1989.tb05291.x

Source DB:  PubMed          Journal:  Br J Urol        ISSN: 0007-1331


  4 in total

Review 1.  Evidence for decreasing quality of semen during past 50 years.

Authors:  E Carlsen; A Giwercman; N Keiding; N E Skakkebaek
Journal:  BMJ       Date:  1992-09-12

2.  Semen analysis standardization: is there any problem in Polish laboratories?

Authors:  Renata Walczak-Jedrzejowska; Katarzyna Marchlewska; Elzbieta Oszukowska; Eliza Filipiak; Leszek Bergier; Jolanta Slowikowska-Hilczer
Journal:  Asian J Androl       Date:  2013-07-01       Impact factor: 3.285

Review 3.  The Disappearing Sperms: Analysis of Reports Published Between 1980 and 2015.

Authors:  Pallav Sengupta; Sulagna Dutta; Elzbieta Krajewska-Kulak
Journal:  Am J Mens Health       Date:  2016-04-19

Review 4.  Evidence for increasing incidence of abnormalities of the human testis: a review.

Authors:  A Giwercman; E Carlsen; N Keiding; N E Skakkebaek
Journal:  Environ Health Perspect       Date:  1993-07       Impact factor: 9.031

  4 in total

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