Literature DB >> 26116103

Ultrasound follow up of an adnexal mass has the potential to save lives.

Eleanor L Ormsby1, Edward J Pavlik2, John R van Nagell2.   

Abstract

Ovarian cancer is among the most dreaded cancers since it is often found at a late stage where the opportunity for extended survival is poor. Ultrasound has been utilized in several ovarian cancer screening trials in asymptomatic women in order to detect ovarian cancer at early stages where survival rates are high. Efforts to improve screening for ovarian cancer are ongoing. While ovarian cancer screening in asymptomatic women is not recommended for clinical application currently, the care of women with adnexal masses found by ultrasound in clinical practice can benefit from close evaluation of the evidence obtained from large prospective ovarian cancer screening trials and by relating this evidence to recent advances in the understanding of different types of ovarian cancer. Post-menopausal women who have an adnexal mass discovered by ultrasound have a much higher risk of developing ovarian cancer than women with normal ultrasound. The preponderance of reported evidence indicates that ultrasound monitoring of an adnexal mass is safe, cost effective and can achieve an improved positive predictive value in detecting ovarian cancer when ovarian abnormalities resolve during surveillance. Proposals to arbitrarily discontinue ultrasound monitoring can negatively impact patient care and generate medical-legal actions, especially because there is no evidence to support safe discontinuation. In this review, we outline a rationale for continuing ultrasound surveillance of ovarian abnormalities.
Copyright © 2015 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  adnexal mass; malignancy; ultrasound

Mesh:

Year:  2015        PMID: 26116103     DOI: 10.1016/j.ajog.2015.06.041

Source DB:  PubMed          Journal:  Am J Obstet Gynecol        ISSN: 0002-9378            Impact factor:   8.661


  4 in total

1.  Risk of Malignant Ovarian Cancer Based on Ultrasonography Findings in a Large Unselected Population.

Authors:  Rebecca Smith-Bindman; Liina Poder; Eric Johnson; Diana L Miglioretti
Journal:  JAMA Intern Med       Date:  2019-01-01       Impact factor: 21.873

Review 2.  Ultrasound Monitoring of Extant Adnexal Masses in the Era of Type 1 and Type 2 Ovarian Cancers: Lessons Learned From Ovarian Cancer Screening Trials.

Authors:  Eleanor L Ormsby; Edward J Pavlik; John P McGahan
Journal:  Diagnostics (Basel)       Date:  2017-04-28

3.  A Perspective on Ovarian Cancer Biomarkers: Past, Present and Yet-To-Come.

Authors:  Frederick R Ueland
Journal:  Diagnostics (Basel)       Date:  2017-03-08

4.  International variation in radiation dose for computed tomography examinations: prospective cohort study.

Authors:  Rebecca Smith-Bindman; Yifei Wang; Philip Chu; Robert Chung; Andrew J Einstein; Jonathan Balcombe; Mary Cocker; Marcos Das; Bradley N Delman; Michael Flynn; Robert Gould; Ryan K Lee; Thomas Yellen-Nelson; Sebastian Schindera; Anthony Seibert; Jay Starkey; Saravanabavaan Suntharalingam; Axel Wetter; Joachim E Wildberger; Diana L Miglioretti
Journal:  BMJ       Date:  2019-01-02
  4 in total

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