BACKGROUND: Symptomatic articular cartilage and osteochondral lesions in the knee are an important source of pain and disability, and may lead to osteoarthritis. There are several surgical treatments for the condition, with emerging data evaluating their clinical effectiveness and longer-term clinical outcome. Health care providers have challenged the indications for the use of expensive techniques and have been reluctant to authorize funding or reimbursement. METHODS: The UK Cartilage Consensus Meeting was convened, involving clinicians in the UK with experience in the treatment options, decision-making and evaluation of the literature on the subject. RESULTS: This paper reports the consensus of attendees regarding appropriate surgical options for managing articular cartilage defects in the knee, validated by a large cohort of surgeons in the UK who are active in the field of articular cartilage surgery. CONCLUSIONS: An evidence-based United Kingdom Consensus of 104 clinicians on the surgical management of symptomatic articular cartilage lesions of the knee. Several techniques may be suitable for small defects. Cell therapy has the best evidence-based outcomes for larger defects. Responsible innovation, pooled data collection and improvement in physical therapies are important. Surgeons should have access to the most appropriate evidence-based therapies for first-line treatment.
BACKGROUND: Symptomatic articular cartilage and osteochondral lesions in the knee are an important source of pain and disability, and may lead to osteoarthritis. There are several surgical treatments for the condition, with emerging data evaluating their clinical effectiveness and longer-term clinical outcome. Health care providers have challenged the indications for the use of expensive techniques and have been reluctant to authorize funding or reimbursement. METHODS: The UK Cartilage Consensus Meeting was convened, involving clinicians in the UK with experience in the treatment options, decision-making and evaluation of the literature on the subject. RESULTS: This paper reports the consensus of attendees regarding appropriate surgical options for managing articular cartilage defects in the knee, validated by a large cohort of surgeons in the UK who are active in the field of articular cartilage surgery. CONCLUSIONS: An evidence-based United Kingdom Consensus of 104 clinicians on the surgical management of symptomatic articular cartilage lesions of the knee. Several techniques may be suitable for small defects. Cell therapy has the best evidence-based outcomes for larger defects. Responsible innovation, pooled data collection and improvement in physical therapies are important. Surgeons should have access to the most appropriate evidence-based therapies for first-line treatment.
Authors: Stephen J Baskey; Marco Andreana; Eric Lanteigne; Andrew Ridsdale; Albert Stolow; Mark E Schweitzer Journal: IEEE J Transl Eng Health Med Date: 2018-12-25 Impact factor: 3.316
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Authors: Giuseppe Filardo; Luca Andriolo; Peter Angele; Massimo Berruto; Mats Brittberg; Vincenzo Condello; Susan Chubinskaya; Laura de Girolamo; Alessandro Di Martino; Berardo Di Matteo; Justus Gille; Alberto Gobbi; Christian Lattermann; Norimasa Nakamura; Stefan Nehrer; Giuseppe M Peretti; Nogah Shabshin; Peter Verdonk; Kenneth Zaslav; Elizaveta Kon Journal: Cartilage Date: 2020-01-15 Impact factor: 3.117
Authors: Maarten P F Janssen; Esther G M van der Linden; Tim A E J Boymans; Tim J M Welting; Lodewijk W van Rhijn; Sjoerd K Bulstra; Peter J Emans Journal: Cartilage Date: 2020-09-15 Impact factor: 4.634